background and aims. lichen planus is a relatively common chronic mucocutaneaous disease with an unknown cause, and is considered a manifestation of cell-mediated immune response. hepatitis c virus (hcv) and its subgroups have been associated with lichen planus in different geographic locations. the present study was undertaken to evaluate the prevalence of hcv antibody in patients with lichen ...

Objectives: Studies done on the management of oral lichen planus using tacrolimus are limited. The aim of the study is to compare the efficacy of tacrolimus with triamcinolone acetonide topically in the management of symptomatic oral lichen planus and also to evaluate adverse effects and opportunistic yeast infections. Materials and methods: A randomized controlled study was conducted on 60 pat...

Background and Aim: Lichen planus is an inflammatory autoimmune mucocutaneous disease. Stimulation of T cells and antigen-presenting cells (APCs), such as dendritic cells, mediates apoptosis of keratinocytes and basement membrane destruction. The aim of this study was to investigate the expression of one of the immune cell markers (CD86) in erosive oral lichen planus. Materials and Methods: In...

Neoplastic transformation (development of squamous cell carcinoma / verrucous carcinoma) in lichen planus has been described, especially in the oral form of the disease where an estimated 0.3-3% of patients may develop squamous cell carcinoma. Malignancy though uncommon with cutaneous lichen planus has been described in chronic hypertrophic lesions of lichen planus on the legs, including a case...

Lichen planus of the male genitalia presents as multiple violaceous papules or discrete annular lesions on the glans or shaft of the penis. In female patients, whitish striae or "leukoplakia-like" patches are occasionally observed on the vestibulum or labia minora and bluish-white papules in the anal cleft or around the anus. Signs of lichen planus elsewhere on the body may be absent. As has be...

Introduction: Lichen planus is a human exclusive, chronic inflammatory disease affecting skin and mucosa, particularly oral mucosa affecting the stratified squamous epithelia. Epithelial alterations in oral lichen planus (OLP) may lead to superimposed Candida infection, especially the normal flora Candida albicans. Therefore, this study was designed to assess the prevalence of Candida infection...

OBJECTIVES Oral lichen planus is chronic inflammatory disease with a high prevalence in the population. This study describes the epidemiological and clinical characteristics of group of patients with oral lichen planus in the Czech Republic. MATERIAL AND METHODS Data was taken from the medical records of 171 patients referred to the Oral Medicine Unit at the University Hospital in Hradec Král...

Oral lichen planus (OLP) has a prevalence of approximately 1%. The etiopathogenesis is poorly understood. The annual malignant transformation is less than 0.5%. There are no effective means to either predict or to prevent such event. Oral lesions may occur that to some extent look like lichen planus but lacking the characteristic features of OLP, or that are indistinguishable from OLP clinicall...

OBJECTIVE To study the relationship between oral lichen planus LP and the habit of chewing deram. METHODS A clinically based controlled observational study including a total of 176 women who used to chew deram and 200 women who never used deram, who consulted the Dermatology Department of Basrah Teaching Hospital, and a private clinic, Barsah, Iraq during the period from February 2005 to July...