نتایج جستجو برای: oral metastatic carcinoma

تعداد نتایج: 682620  

Journal: :Egyptian Journal of Radiology and Nuclear Medicine 2022

Abstract Background The unilateral submandibular gland aplasia (agenesis) is a rare, asymptomatic condition usually discovered incidentally on imaging. This associated commonly with either compensatory hypertrophy of contralateral or sublingual glands. Case presentation We report the case 34-year-old male detected ipsilateral gland, demonstrated by imaging modalities, where we have highlighted ...

Journal: :Molecular cancer research : MCR 2009
Ming-Heng Wu Tse-Ming Hong Hui-Wen Cheng Szu-Hua Pan Yu-Ray Liang Hsiao-Chin Hong Wei-Fan Chiang Tung-Yiu Wong Dar-Bin Shieh Ai-Li Shiau Ying-Tai Jin Yuh-Ling Chen

Galectin-1 (Gal-1) is a beta-galactose-binding lectin; its expression level has been reported to correlate with tumor progression. Gal-1 is highly expressed in the invasive front of primary tumors and in the cancer cells of metastatic lesions in the lymph nodes of patients with oral squamous cell carcinoma. However, the molecular mechanism of Gal-1 in tumor metastasis is not completely clear. W...

Journal: :The Kobe journal of medical sciences 2010
Masahiro Umeda Tsutomu Minamikawa Takashi Shigeta Akiko Oguni Tomoko Kataoka Hidenori Takahashi Yasuyuki Shibuya Takahide Komori

Cancer of the tongue or the floor of the mouth sometimes metastasizes to the lingual lymph node. We present two patients with squamous cell carcinoma of the floor of the mouth who developed metastases to the lateral lingual lymph nodes. Case 1, a 62-year old male, had squamous cell carcinoma of the floor of the mouth (T3N2cM0). He underwent tumor resection and bilateral neck dissection, and his...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2002
Jeffrey N Myers F Christopher Holsinger Samar A Jasser B Nebiyou Bekele Isaiah J Fidler

PURPOSE Despite advances in our understanding, prevention, and treatment of head and neck squamous cell carcinoma (SCC), the 5-year survival rates for patients remain low. This poor prognosis for head and neck SCC and SCC of the oral tongue (SCCOT) in particular reflects a limited understanding of the mechanisms of local and regional metastasis, which accounts for a majority of deaths. To analy...

2016
ZHEN CAI CHAO ZHU LIZHEN WANG LING ZHU ZHIYUAN ZHANG HANGUANG ZHU YAN'AN WANG

Mandibular metastatic carcinoma is a rare lesion that accounts for <1% of all oral malignancies. To provide greater experience in this field, the present study was conducted in which 6 cases of mandibular metastatic carcinoma were retrospectively reviewed. The origin of the lesions was the prostate in 2 cases, the lungs in 2 cases, the breast in 1 case and the thyroid gland in 1 case. The clini...

Journal: :International journal of oral and maxillofacial surgery 2009
R Munakata F A Sawair J Cheng T Saku

Diagnosing gingival metastases is difficult because clinically they can mimic benign oral lesions. The authors report an unusual case of metastatic ovarian carcinoma in the gingiva of a 46-year-old woman 5 years after ovariectomy. The tumor presented as an exophytic growth at the molar region of the mandible. Histological examination showed invasive proliferation of atypical glandular structure...

2011
Ana M. Molina Michelle S. Ginsberg Robert J. Motzer

A 70-year-old man with metastatic renal cell carcinoma developed progressive liver metastases after 8 weeks of treatment with the multitargeted tyrosine kinase inhibitor (TKI) sunitinib. He then participated in the phase III placebo-controlled clinical trial of the oral mammalian target of rapamycin (mTOR) inhibitor everolimus, initially randomized to placebo (but had disease progression after ...

2016
Levi G. Ledgerwood Dhruv Kumar Agda Karina Eterovic Jo Wick Ken Chen Hao Zhao Loubna Tazi Pradip Manna Spencer Kerley Radhika Joshi Lin Wang Simion I. Chiosea James David Garnett Terance Ted Tsue Jeremy Chien Gordon B. Mills Jennifer Rubin Grandis Sufi Mary Thomas

In an era where mutational profiles inform treatment options, it is critical to know the extent to which tumor biopsies represent the molecular profile of the primary and metastatic tumor. Head and neck squamous cell carcinoma (HNSCC) arise primarily in the mucosal lining of oral cavity and oropharynx. Despite aggressive therapy the 5-year survival rate is at 50%. The primary objective of this ...

Journal: :acta medica iranica 0
sanambar sadighi cancer research center, cancer institute of iran, tehran university of medical sciences, tehran, iran. amanolah keyhani department of head and neck surgical oncology and reconstructive surgery, cancer institute of iran, tehran university of medical sciences, tehran, iran. iraj harirchi department of head and neck surgical oncology and reconstructive surgery, cancer institute of iran, tehran university of medical sciences, tehran, iran. ata garajei department of head and neck surgical oncology and reconstructive surgery, cancer institute of iran, tehran university of medical sciences, tehran, iran. mahdi aghili radiotherapy oncology research center, cancer institute of iran, tehran university of medical sciences, tehran, iran. ali kazemian radiotherapy oncology research center, cancer institute of iran, tehran university of medical sciences, tehran, iran.

to evaluate the effect of adding neoadjuvant chemotherapy to surgery and radiation therapy for locally advanced resectable oral cavity squamous cell carcinoma, 24 patients with t3 or t4a oral cavity squamous cell carcinoma were randomly assigned to surgery alone or docetaxel, cisplatin, and 5-fu (tpf) induction chemotherapy followed by surgery. all patients were planned to receive chemoradiothe...

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