in vitro assessment of the antifungal activities was evaluated in the present study for both aqueous and ethanol extracts prepared from leaves of avicennia marina and rhizophora mucronata . leaves of mangrove species were collected from qeshm and syrik of south-east coast of iran, mangrove forest respectively. antimicrobial tests were carried out through disk diffusion method. minimum fungicida...

Candida albicans infections range from superficial to systemic and are one of the leading causes fungus-associated nosocomial infections. The innate immune responses during these various infection types differ, suggesting that host environment plays a key role in modulating host–pathogen interaction. In addition, C. is able remodel its cell wall response environmental conditions evade clearance...

Candida albicans, the major invasive fungal pathogen of humans, can cause both debilitating mucosal infections and fatal invasive infections. Understanding the complex nature of the host-pathogen interaction in each of these contexts is essential to developing desperately needed therapies to treat fungal infections. RNA-seq enables a systems-level understanding of infection by facilitating comp...

The cytoplasmic helicase RIG-I is an established sensor for viral 5'-triphosphorylated RNA species. Recently, RIG-I was also implicated in the detection of intracellular bacteria. However, little is known about the host cell specificity of this process and the bacterial pathogen-associated molecular pattern (PAMP) that activates RIG-I. Here we show that RNA of Salmonella enterica serovar Typhim...

The oral ecosystem is strictly related to a balance maintained by specific niches recognized as sites, where oral bacteria can metabolize avoiding the immune system response. The oral bacteria species that colonize the ecological niches vary during fixed orthodontic treatment, with a prevalence of periodontal bacterial species. Qualitative analysis of five periodontal pathogens was used to inve...

The oral mucosa is an important interface for host-environment interactions. Based on previous studies, it is generally accepted that the cellular compartments of the oral immune system comprise organized mucosal-associated lymphoid tissues as well as diffusely and focally distributed T- and to lesser extent B-lymphocytes, oral mucosal Langerhans cells (OMLC), macrophages and mast cells. Howeve...

This review discusses the principles of constructing epidemiological classifications infectious diseases. A rationale is provided that taxonomy correspond to a combination morphological and functional approaches. The former covers shape symmetry parasites, while latter based on pathogen transmission mechanisms or ‘function-and-energy’ approach. idea are an evolutionary tool implemented in epide...

Respiratory diseases are responsible for a significant number of deaths and considerable suffering in humans. Accumulating evidence suggests that oral disorders, particularly periodontal disease, may influence the course of respiratory infections like bacterial pneumonia and chronic obstructive pulmonary disease (COPD). Oral periodontopathic bacteria can be aspirated into the lung causing aspir...