BACKGROUND Oral submucous fibrosis (OSF), a potentially malignant oral lesion, is a form of pathological fibrosis affecting the oral mucosa. It results from an imbalance in equilibrium of the normal process of synthesis and degradation of extra cellular matrix. Matrix metalloproteinases and its inhibitors play important role in remodeling of the extra cellular matrix which are important in prog...

OBJECTIVES To evaluate the efficacy of oral lycopene therapy in patients with oral submucous fibrosis and to compare these effects with a placebo. STUDY DESIGN Fifty-eight patients with oral submucous fibrosis formed the population for the study and were randomly divided into 3 groups, evaluated weekly over a 2-month period. Patients of group A (n = 21) received 16 mg of lycopene, those of gr...

Aim: To evaluate the Clinico-Demographic variables in patients of Oral Submucous Fibrosis
 Study Design: Descriptive Cross Sectional
 Place and Duration Study: Department Maxillofacial Surgery, Liaquat Medical University Hospital from December 2017 to February 2019.
 Methodology: The recruitment was done after clinical diagnosis oral sub mucous fibrosis (OSMF) patients. demograph...

BACKGROUND AND OBJECTIVES Oral submucous fibrosis (OSF) is a chronic condition of the oral cavity which results in permanent disability. A number of studies have proven that the management of premalignant diseases should include antioxidants. Therefore, a study was carried out to evaluate the efficacy of spirulina as an antioxidant adjuvant to corticosteroid injections in the management of 40 o...

Oral submucous fibrosis (OSMF) is a chronic, insidious and disabling condition affecting the oral cavity, being especially prevalent in India and South East Asia. However, considering its high prevalence and potential to undergo malignant transformation, OSMF has not been widely investigated with respect to levels of antioxidants, especially beta carotene. In the present study, an attempt was m...

Background and aims. Many oral squamous cell carcinomas develop from potentially malignant disorders (PMDs)which include a variety of lesions and conditions characterized by an increased risk for malignant transformation. Thisstudy evaluated the quantitative expression of EGFR in normal oral mucosa, oral leukoplakia and oral submucous fibrosis to predict the malignant risk in compliance with th...

Abstract Mycobacterium abscessus appears to be increasing cause of pulmonary infection in children with underlying risk factors including cystic fibrosis, chronic lung disease and immunodeficiency syndromes. We present a case M. pediatric patient primary ciliary dyskinesia he was successfully treated parenteral amikacin, linezolid oral clarithromycin combined inhaled amikacin. Clinical improvem...

background: keratinocyte growth factor (kgf) is a potent epithelial mitogen that acts by binding the kgf receptors (kgfrs) expressed on epithelial cells and regulates proliferation and differentiation. the objective of this study was to investigate the expression of kgf in the epithelium in oral precancer. materials and methods: archival tissues of oral submucous fibrosis (smf) and leukoplakia ...