Hydroa vacciniforme (HV) is a rare acquired photodermatosis, usually with onset in childhood and characterized by vesicles, crust and scar formation that follow exposure to sunlight.Vacciniform scars of face and dorsa of the hands are common features but oral ulcer and eye signs also rarely occur. It usually resolves before adult age. A rare manifestation of the disease would be persisten...

The objective of this study was to investigate the antiulcer activity of leaves of Aspilia africana C.D. Adams (Compositae) in rats. Fresh dried leaves of A. africana were extracted by hot water maceration and the yield freeze dried. Antiulcer effects of the aqueous extract at 25, 50 and 100 mg/kg were evaluated in rats using ethanol, indomethacin and aspirin induced ulcer methods. Phytochemica...

The gastro-protective and antioxidant effects of methanol extract of Ficus asperifolia bark on indomethacin induced gastric ulcer were investigated in male rats. Thirty two male rats divided into 4 equal groups and were treated as follows: group1 (control), 0.5ml of 5% tween 80 (vehicle for the extract), groups 2 and 3, 100 and 500mg/kg of Ficus asperifolia extract respectively and group 4, cim...

This research aimed to determine the potential protective effects ofPhaleria macrocarpafruit extracton rat gastric mucosal injury induced by ethanol andto clarify the roles of prostaglandinE2 (PGE2), transforming growth factor1 (TGF) and tumor necrosis factorTNF). Main methods: Seven groups of rats were orally pretreated with Tween20 as vehicle control group; Tween20 as ulcer group; 20 mg/kg of...

Most of the currently available oral antiulcer drugs for the treatment of peptic ulcer provoke detrimental adversative effects. Hence, the exploration for plant-derived products for the treatment of ulcer continues. Syringin, a phenylpropanoid glucoside found in the tepals of Musa Paradisiaca, has many biological properties, including as an antioxidant, immunomodulatory and antidiabetic agent. ...

The present study was performed to evaluate the anti-ulcerogenic activity of ethanol extract of Centella asiatica against ethanol-induced gastric mucosal injury in rats. Five groups of adult Sprague Dawley rats were orally pre-treated respectively with carboxymethyl cellulose (CMC) solution (ulcer control group), Omeprazole 20 mg/kg (reference group), and 100, 200 and 400 mg/kg C. asiatica leaf...

BACKGROUND & AIMS Nutrients putatively implicated in pressure ulcer healing were evaluated in a clinical setting. METHODS Sixteen inpatients with a stage 2, 3 or 4 pressure ulcer randomised to receive daily a standard hospital diet; a standard diet plus two high-protein/energy supplements; or a standard diet plus two high-protein/energy supplements containing additional arginine (9 g), vitami...