Cancer cells, besides reproducing uncontrollably, lose cohesiveness and orderliness of normal tissue, invade and get detached from the primary tumor to travel and set up colonies elsewhere. Dislodging neoplastically altered cells from a tumor during biopsy or surgical intervention or during simple procedure like needle aspiration is a possibility because they lack cohesiveness, and they attain ...

M.D., F.R.C.P., and M. Mitman, M.D., F.R.C.P., with the collaboration of Ian Taylor M.D., M.R.C.P. Fourth edition. (Pp. 698. 30s.). Edinburgh: E. & S. Livingstone. 1951. I HE fourth edition of this wvork, first printed in 1940, enhances the positioIn enjoyed by its earlier editions. TIhe presentation of the current teaching of infectious diseases is commendable for its orderliness. Followving c...

The phenomenon of /l/-darkening has been a subject of linguistic interest due to the remarkable amount of contextual variation it displays. Although it is generally stated that the light variant occurs in onsets (e.g. leap) and the dark variant in codas (e.g. peel), many studies report variation in different morphosyntactic environments. Beyond this variation in morphosyntactic conditioning, di...

The neuroendocrine mechanisms by which estradiol drives growth hormone (GH) secretion in the human are poorly defined. Here we investigate estrogen's specific regulation of the 24-h pulsatile, nyctohemeral, and entropic modes of GH secretion in healthy postmenopausal women. Volunteers ( n = 9) received randomly ordered placebo versus estradiol-17β (1 mg micronized steroid twice daily orally) tr...

This study examined trajectories of aggression and rule breaking during the transition from childhood to adolescence (ages 9-15), and determined whether these trajectories were predicted by lower order personality facets, overreactive parenting, and their interaction. At three time points separated by 2-year intervals, mothers and fathers reported on their children's aggression and rule breakin...

The preovulatory luteinizing hormone (LH) surge results from the integration of complex interactions among gonadal steroids and hypothalamic and pituitary hormones. To evaluate changes in LH secretory dynamics that occur during the rat LH surge, we have 1) obtained frequently sampled serum LH concentration time series, 2) used both waveform-dependent and waveform-independent convolution analyse...

The world around us presents two fundamentally different forms of patterns: those that appear random and those that appear ordered. As adults we appreciate that these two types of patterns tend to arise from very different sorts of causal processes. Typically, we expect that, whereas agents can increase the orderliness of a system, inanimate objects can cause only increased disorder. Thus, one ...

Testosterone (T) secretion declines in the aging male, albeit for unknown reasons. From an ensemble perspective, repeated incremental signaling among gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH), and T is required to maintain physiological androgen availability. Pattern-regularity statistics, such as univariate approximate entropy (ApEn) and bivariate cross-ApEn, provide spec...

OBJECTIVE Spontaneous parathyroid hormone (PTH) secretory dynamics include tonic and pulsatile components. It is not known how glucocorticoids might alter these secretory dynamics. DESIGN The aim of our study was to evaluate spontaneous fluctuations in serum PTH levels in six adult male patients (aged 31-64 years) receiving chronic (>6 months) therapy with glucocorticoids (daily dosage >7.5 m...

Based on the research of domestic and foreign scholars, this paper has improved and established a double oligopoly market model of renewable energy, and analyzed the complex dynamic characteristics of a system based on entropy theory and chaos theory, such as equilibrium point, stability, Hopf bifurcation conditions, etc. This paper also studied and simulated the effects of the natural growth r...