objective: fragile x syndrome is the second etiology for inherited mental retardation. it may concomitant with other psychiatric disorders. intellectual disability (id) is a state of functioning that typically begins in childhood and is characterized by limitations in intelligence and adaptive skills. we intend to introduce a male young patient with fragile x syndrome and obsessive-compulsive d...

abstract acute inflammation of the gallbladder can occur without gallstones. acalculous cholecystitis typically develops in critically ill patients in the intensive care unit. patients on parenteral nutrition, with extensive burns, sepsis, major operations, multiple organ trauma or prolonged illness with multiple organ system failure are at risk for developing acalculous cholecystitis. the asso...

CHARGE syndrome is a complex developmental disorder caused by mutations in the chromodomain helicase DNA-binding gene CHD7. Kabuki syndrome, another developmental disorder, is characterized by typical facial features in combination with developmental delay, short stature, prominent digit pads and visceral abnormalities. Mutations in the KMT2D gene, which encodes a H3K4 histone methyltransferase...

Opsoclonus-myoclonus-ataxia syndrome is a heterogeneous constellation of symptoms ranging from full combination these three neurological findings to varying degrees isolated individual sign. Since the emergence coronavirus disease 2019 (COVID-19), symptoms, syndromes, and complications associated with this multi-organ viral infection have been reported various aspects involvement are increasing...

objective: premenstrual syndrome (pms) is a cluster of physical and emotional changes that typically begins several days before the menstrual period that disappears quickly after menstruation. it seems that cooccurrence of depression increases the risk and severity of this syndrome. in this cross-sectional research, we evaluated an association between pms and depression in medical students. met...

background: polycystic ovary syndrome (pcos) is a heterogeneous complex genetic disorder characterized by hyperandrogenemia hyperinsulinemia insulin resistance and chronic anovulation. it is the most common endocrine disorder in women of reproductive age with an enigmatic pathophysiologic and molecular basis. obesity hyperandrogenism and infertility occur frequently in pcos which mostly have a ...

melas syndrome is a mitochondrial disorder with progressive nature, because adequate treatment is not available. diagnosis of this mitochondrial disorder depends initially on clinical suspicion, which is strengthened by additional metabolic evidence of impaired oxidative metabolism such as high serum or c.s.f. lactate levels and confirmed by demonstration of mitochondrial abnormalities-in muscl...

The current issue of the Iranian Rehabilitation Journal contains original research evaluating the efficacy of addiction rehabilitation an evaluation of a child rehabilitation system for community based research, reading program for children with down syndrome, auditory stream segregation in auditory processing disorder, speech and language disorders, quality of life of adolescents with hearing ...

IMPORTANCE Purkinje cell cytoplasmic antibody type 1 (PCA-1)-IgG (or anti-Yo) is characteristically detected in women with gynecological or breast adenocarcinoma. We describe 2 unique scenarios occurring in 1 patient: PCA-1 paraneoplastic autoimmunity in a child, and a paraneoplastic neurological disorder in the context of Down syndrome. OBSERVATIONS A child with Down syndrome and a history o...