Case 1. A full-term male child, weighing 6j lb., the product of a second pregnancy, was born on Aug. 3, 1945. The parents were unrelated. When three months old the child was thought to be blind, and two months later on x-ray examination a diagnosis of osteopetrosis was made. Mental retardation was noted at ten months. At two years two months he was admitted to the Royal Blind School; he was a w...

Osteopetrosis is an inherited bone disorder characterized by general skeletal sclerosis. The cortex and spongiosa are increased in thickness and density. and the bone marrow spaces are reduced in volume [1]. Histopathologically, excessive retention of chondroosseous tissue and failure of remodeling of bones are the result of retarded osteocytic osteolysis and osteocytic chondrolysis [2] . Signs...