Mice have been used in ovarian cancer research mainly as hosts for cell lines derived from human ovarian tumors and ascites. Such models provided valuable information into the nature of metastatic ovarian cancer and possible treatment strategies. However, the complexity of genetic aberrations in human ovarian cancer cell lines precluded understanding of the initiating events responsible for ova...

BACKGROUND P63 immunostaining has been considered as potential prognostic factor in laryngeal cancer. Considering that P63 is mainly nuclear stain, a possible correlation between the texture of P63-stained nuclei and the tumor's grade could be of value to diagnosis, since this may be related to biologic information imprinted as texture on P63 expressed nuclei. OBJECTIVE To investigate the ass...

objective: to determine the efficacy of ovarian drilling in pco patients who failed to achieve pregnancy with medical treatment. methods and main results: 75 patients with a diagnosis of pco of whom 48(64%) were primary infertile and 27(36%) were secondary infertile were clomiphene resistant. the other methods like bromocriptin, gonadotropins, gnrh -a and metformin had been given to these patie...

background: ovarian masses represent a range of pathology from benign cyst to highly aggressive malignant tumors. it has been estimated that gynecologic malignancy account for approximately 2% of all types of cancer in children, 60-70% of these lesions arise in the ovary.  methods: all ovarian masses which were resected or biopsied in mofid children's hospital from 2002 to 2012 were review...

Ovaries are hormone influence organs and make a base for related diseases. Many other lesions are also seen in ovaries which are not related to hormonal disturbance. Ovarian lesions are not diagnosed in early stages as they are asymptomatic and physically difficult to examine. Though the non neoplastic lesions are very common when compared to neoplastic lesions of the ovary, there are very few ...

Endometriosis is a common benign gynecologic disorder, defined by endometrial glands and stroma outside of the endometrial cavity. The three primary types of endometriosis are superficial peritoneal lesions, ovarian endometriomas, and deep infiltrating endometriosis (DIE).Although laparoscopy continues to be the gold standard for the diagnosis of endometriosis, transvaginal ultrasonography show...

We report on a rare case of sarcoidosis that developed after chemotherapy for ovarian cancer, and mimicked a cancer metastasis. A 52-year-old female diagnosed with stage III ovarian cancer underwent curative surgery and postoperative chemotherapy. Four months later, her whole-body positron emission tomography and computed tomography (CT) scan showed high uptake in the mediastinal lymph nodes, a...

Ovarian cystic masses include a spectrum of benign, borderline and high grade malignant neoplasms. Imaging plays a crucial role in characterization and pretreatment planning of incidentally detected or suspected adnexal masses, as diagnosis of ovarian malignancy at an early stage is correlated with a better prognosis. Knowledge of differential diagnosis, imaging features, management trends and ...