The mammalian ovary is composed of ovarian follicles, each follicle consisting of a single oocyte surrounded by somatic granulosa cells, enclosed together within a basement membrane. A finite pool of follicles is laid down during embryonic development, when oocytes in meiotic arrest form a close association with flattened granulosa cells, forming primordial follicles. By or shortly after birth,...

Objective – To assess the precision of individual ovarian volume measurements by 2D and 3D transvaginal ultrasound scan. Study Design – Transvaginal 2D and 3D ultrasound examinations were performed on 49 women attending a tertiary centre for investigation or treatment for subfertility. Two observers calculated ovarian volume, using both the prolate ellipsoid formula and virtual organ computer-a...

Effect of exposure to constant light (CL), blinding and olfactory bulbectomy (OBX) on reproduction of adult and weanling female Tatera indica cuvieri was investigated. In adult females, CL induced changes in estrus cyclicity. Weanlings subjected to CL showed reduced ovarian weight. Blinding did not bring about changes in estrus cyclicity and reproductive organ weight (ovary and uterus) of eithe...

The epithelial ovarian carcinomas, which make up more than 85% of human ovarian cancer, arise in the ovarian surface epithelium (OSE). The etiology and early events in the progression of these carcinomas are among the least understood of all major human malignancies because there are no appropriate animal models, and because methods to culture OSE have become available only recently. The object...

BACKGROUND CORNEAS NEEDED FOR KERATOPLASTY CAN BE HARVESTED USING TWO TECHNIQUES: whole globe enucleation and in situ excision of the corneoscleral disc. This study evaluates the rate of microbial contamination of the donor cornea organ culture medium according to the method of retrieval. METHODS All donor corneas of our cornea bank received between January 1, 2001 and December 31, 2009 put i...

Fertility results from coordinate functioning of components of the hypothalamic-pituitary-ovarian-genital axis. In normal women, ovarian sex steroid hormones act as the mediators of these interactions.Infertility is a clinical manifestation of the failure of one or more of the components to function appropriately. Determining the locus of dysfunction provides the basis for rational treatment. F...