OBJECTIVE The aim of this study was to elucidate the etiology and treatment of primary ovarian insufficiency, which is of unknown cause in 95% of the cases. MATERIALS AND METHODS Thirty patients aged 18-40 years who presented to Dicle University Faculty of Medicine Clinic of Obstetrics and Gynecology between June 2012 and January 2014 and were diagnosed as having primary ovarian insufficiency...

background: the present study was carried out to investigate the possible protective effects of royal jelly (rj) on oxymetholone (oxm)-induced oxidative liver injuries in mice. methods: in total, 32 adult male nmri mice were divided into four groups of eight mice each. mice in groups 1 and 2 were orally administered 5 mg/kg/day oxm for 30 days. at the same time, mice in group 3 received rj at a...

conclusions with regard to the potent antioxidant properties of silymarin, the neuroprotective effects of this natural compound suggested in the current study may in part be mediated through inhibition of oxidative stress. results exposure to acr reduced cell viability in pc12 cells. pre-treatment of cells with silymarin (100 µm) significantly reduced acr-induced toxicity. in addition, administ...

in the present study, free-radical-scavenging and antioxidant activities of angipars™, an herbal extract which has been registered as a therapeutic drug for diabetic foot ulcer, were examined. we investigated the protective effect of angipars™ on cytotoxicity produced by exposure to h2o2 (300 µm) in hepg2 and a549 cell lines, using mtt assay, glutathione (gsh) content analysis, and lipid peroxi...

propionic acid (pa) is a short chain fatty acid, a common food preservative and metabolic end product of enteric bacteria in the gut. the present study was undertaken to investigate the effect of pa on liver injury in male rats. male western albino rats were divided into two groups. the first group served as normal control, the second was treated with pa. the activities of serum hepatospecific ...

background: oxidative stress plays an important role in the pathogenesis and progression of γ-irradiation-induced cellular damage, lung is a radiosensitive organ and its damage is a dose-limiting factor in radiotherapy. the administration of dietary antioxidants has been suggested to protect against the succeeding tissue damage. the present study aimed to evaluate the radioprotective efficacy o...

OBJECTIVE Oxidative stress plays a major role in the development of atherosclerosis. However, the relationship between oxidative stress and complexity and intensity of coronary artery disease is less clear. The aim of this study is to assess the relationship between oxidative stress markers and the complexity and intensity of coronary artery disease in patients with acute coronary syndrome (ACS...