CYP83B1 from Arabidopsis thaliana has been identified as the oxime-metabolizing enzyme in the biosynthetic pathway of glucosinolates. Biosynthetically active microsomes isolated from Sinapis alba converted p-hydroxyphenylacetaldoxime and cysteine into S-alkylated p-hydroxyphenylacetothiohydroximate, S-(p-hydroxyphenylacetohydroximoyl)-l-cysteine, the next proposed intermediate in the glucosinol...

1-(3-(Pyridin-2-yl)phenyl)methanamine derivatives have been synthesized and underwent C–H bond activation to afford unsymmetrical NCN’ pincer palladacycles, which were characterised in the solid state. 2-Pyridinyl-phenol and -benzyl alcohols were then used as precursors to unsymmetrical PCN pincer palladacycles. Catalytic applications, where the palladacycle remains in the Pd(II) state, have be...

Catalytic hydrogenation of nitrocyclohexane could be an alternative source various useful chemicals: cyclohexanone oxime, cyclohexanone, cyclohexanol, cyclohexylamine and dicyclohexylamine.

Complexes [Pd{C,N-Ar{C(Me)=NOH}-2}(μ-Cl)](2) (1) with Ar = C(6)H(4), C(6)H(3)NO(2)-5 or C(6)H(OMe)(3)-4,5,6, were obtained from the appropriate oxime, Li(2)[PdCl(4)] and NaOAc. They reacted with neutral monodentate C-, P- or N-donor ligands (L), with [PPN]Cl ([PPN] = Ph(3)P=N=PPh(3)), with Tl(acac) (acacH = acetylacetone), or with neutral bidentate ligands N^N (tetramethylethylenediamine (tmeda...

A set of oxime carbamates having N-alkyl and N,N-dialkyl substituents were prepared via carbonyldiimidazole intermediates. It was shown by EPR spectroscopy that they underwent clean homolysis of their N-O bonds upon UV photolysis. During photolysis of acetophenone O-allylcarbamoyl oxime, the corresponding oxazolidin-2-onylmethyl radical was detected by EPR spectroscopy, providing the first evid...

This review summarizes the new carbon-carbon bond construction methods based on the radical reaction of imine derivatives. The intermolecular carbon radical addition to oxime ethers proceeded smoothly in the presence of BF3.OEt2. A high degree of stereocontrol in the reaction of oxime ethers was achieved to give amino acid derivatives with excellent diastereoselectivities. The radical reaction ...

A novel photoredox-catalyzed C(sp 3 )–C(sp ) cross-coupling between N -arylamines and cycloketone oxime esters under mild conditions has been accomplished.