Abstract Study question To investigate the influence of paternal age on live birth rates in oocyte recipient cycles Summary answer Increased appears to have a negative impact when adjusted for sperm quality. What is known already While effect maternal ART outcomes well established, unclear. Even systematic reviews assessing yielded conflicting results. Morris et al., 2020 could not demonstrate ...

Severe pruritus in atopic dermatitis (AD) significantly impairs patients’ quality of life, primarily due to relentless itching. Sensory nerves the epidermis are important mediating sensation itch, but there is conflicting evidence whether epidermal nerve density increased or decreased lesional skin AD. Here we measured length, branching, and neurotransmitter expression healthy controls non-lesi...

Background: Recent evidence shows that epileptiform activity (EA) in sleep can present early Alzheimer’s Disease (AD) with faster cognitive decline. Existing literature examining sleep, AD and seizures is mostly qualitative. We conducted a systematic review to quantify the stage most associated EA amnestic mild impairment (aMCI)Methods: searched MEDLINE Embase using MeSH terms: “Alzheimer’s Dis...