Bilharzial-related bladder carcinoma (BBC) is the most common malignant neoplasm in Egypt, also occurring with a high incidence in other regions of the Middle East and East Africa. The clinical and pathological features of BBC are different than those described for the conventional transitional cell carcinoma of the bladder, including the high incidence of squamous cell carcinoma reported in BB...

Background: Meningioma is among the most common slow growing central nervous neoplasms, which recurs locally despite the benign histologic features. The aim of this study was to evaluate osteopontin and ki67 expressions in different histologic grades of meningioma in a group of Iranian people. Methods: In this cross-sectional study, first, the paraffin blocks with the definite pathological dia...

Mục tiêu: Mô tả một số đặc điểm lâm sàng, X-quang và sự bộc lộ dấu ấn miễn dịch Ki67 p53 trong các u thần kinh nội tiết của phổi. Đối tượng phương pháp nghiên cứu: mô cắt ngang, chọn mẫu thuận tiện. Kết quả: U phổi thường gặp ở nam giới hút thuốc tuổi ≥ 60 (52%); trung bình là 59,5±8,6 tuổi. Triệu chứng hay nhất đau ngực mệt mỏi, gầy sút cân. Phần lớn thùy trên, kích thước > 3cm. Dấu dương t...

We explain the state of the art of the immunohistochemical markers of response in rectal cancers treated with neoadjuvant medical therapies and its implication with prognosis. Neoadjuvant chemoradiotherapy is widely used to improve the outcome of patients with locally advanced rectal cancer, and the evaluation of the effects of medical therapy is to date based on histomorphological examination ...

UNLABELLED Epidermoid carcinomas represent from 90% to 95% of oral cavity malignant neoplasias, making up 13,470 cases/year. AIMS To correlate p53 and Ki-67 expressions in mouth and tongue carcinomas with lymph node status, gender, histological grade, tumor volume and pathological stage. MATERIALS AND METHODS We carried out a retrospective study of 28 cases of mouth and tongue epidermoid ca...

5-Fluorouracil (5FU)-based therapy is given to patients with advanced colorectal cancer and as adjuvant treatment. Thymidylate synthase (TS) is the target for 5FU, and may have a prognostic role for the outcome of 5FU-based therapy together with proliferation markers such as p53 and Ki67. Thymidine phosphorylase (TP, also known as platelet-derived endothelial cell growth factor) may be of impor...

OBJECTIVE Paratesticular tumors, which comprise a heterogeneous group of entities, are often described in case reports in the literature. In this study, we present histomorphological, immunohistochemical and clinical features of six cases with paratesticular sarcoma. MATERIAL AND METHODS Six cases with paratesticular sarcoma diagnosed in our hospital between 1997 and 2012 were included in thi...

Colorectal cancer (CRC) is one of the most frequent cancers worldwide and shows rapidly rising trend globally. Biological characteristics govern clinical outcome cancer. Over period 11 years (2008 to 2018) totals 435 patients colorectal were reported their tumour blocks complete set information was available for 201 patients. Immunohistochemistry done ER, PR, HER 2-neu, Ki-67, Bcl-2, E-Cadherin...