Ubiquitin is important for the release of human immunodeficiency virus type 1 (HIV-1) and several other retroviruses, but the functional significance of Gag ubiquitination is unknown. To address this problem, we decided to analyze Gag ubiquitination in detail. A low percentage of the HIV-1 p6 protein has previously been shown to be ubiquitinated, and published mutagenesis data suggested that Ga...

We implement the Predicting Particles Produced in Power-Plant Plumes (P6) sub-grid sulphate parameterization for the first time into a global chemical-transport model with online aerosol microphysics, the GEOS-Chem-TOMAS model. Compared to simulations using two other previous treatments of sub-grid sulphate, simulations using P6 subgrid sulphate predicted similar or smaller increases (depending...

High resolution data have high relief displacement in hilly terrains. Development of Digital Elevation model helps to assess bio resources more accurately in such terrains. While estimating bio resources in the Himalayan hilly terrain using multispectral LISS-III data of 23 m spatial resolution, the need for orthorectifcation of satellite data was necessary to correct for spatial distances due ...

We theoretically propose that hexagonal silicon-based crystals, $P6/m$-Si$_6$ and $P6/m$-NaSi$_6$, are topological Dirac semimetals with superconducting critical temperatures of 12 K 13 K, respectively, at ambient pressure. Band inversion occurs the Fu-Kane invariant $\mathbb{Z}_2=1$, even in absence spin-orbit coupling. The nodes protected by $C_6$ crystal rotational symmetry remain gapless Us...

Atopic dermatitis (AD) is a common pruritic inflammatory disease triggered by a defective skin barrier and immunodysregulation. AD has been considered a typical example of a Th2 response associated with allergic disease. In the early phases of the disease, symptoms include IgE hyperproduction, eosinophil accumulation, and mast cell activation; in the chronic phase, a Th1-dominant immune respons...

myo-Inositol-1,2,3,4,5,6-hexakisphosphate (Ins P6) was first described as an abundant form of phosphorus in plant seeds and other plant tissues and dubbed ‘‘phytic acid’’. Subsequently it was found to be a common constituent in eukaryotic cells, its metabolism a basic component of cellular housekeeping. In addition to phosphate, myo-inositol (Ins) and mineral storage and retrieval in plant orga...