BACKGROUND This study was conducted to evaluate the expression of the activated leukocyte cell adhesion molecule (ALCAM) in pancreatic cancer (PAC) and to determine whether or not the ectodomain shedding of ALCAM (s-ALCAM) could serve as a biomarker in the peripheral blood of PAC patients. MATERIAL AND METHODS Tissue specimens and blood sera of patients with PAC (n = 264 and n = 116, respecti...

The VPAC(1) and VPAC(2) receptors for vasoactive intestinal polypeptide and the PAC(1) receptor for pituitary adenylate cyclase-activating polypeptide are members of a subfamily of G protein-coupled receptors (GPCRs). We recently reported that phospholipase D (PLD) activation by members of the rhodopsin group of GPCRs occurs by at least two routes, one of which seems to involve the small G prot...

Abstract Polyaluminium chloride (PAC) with different basicity is used as a coagulant in most drinking water treatment plants (WTP). The aluminium concentration PAC and its hydrolysis mechanism varied the of PAC. Incremental addition changes various physico-chemical properties turbidity removal mechanisms water. Water use beyond optimum dose without considering other aspects, including residual ...

The hydrolysis/precipitation behaviors of Al(3+), Al(13) and Al(30) under conditions typical for flocculation in water treatment were investigated by studying the particulates' size development, charge characteristics, chemical species and speciation transformation of coagulant hydrolysis precipitates. The optimal pH conditions for hydrolysis precipitates formation for AlCl(3), PAC(Al13) and PA...

Xenogeneic chondrocytes and allogeneic mesenchymal stem cells (MSC) are considered a potential source of cells for articular cartilage repair. We here assessed the immune response triggered by xenogeneic chondrocytes when injected intraarticularly, as well as the immunoregulatory effect of allogeneic bone marrow-derived MSC after systemic administration. To this end, a discordant xenotransplant...

OBJECTIVES To evaluate the clinical and cost-effectiveness of managing critically ill patients in adult, general intensive care with or without pulmonary artery catheters (PACs). DESIGN An open, multi-centre, randomised controlled trial with economic evaluation (cost-utility and cost-effectiveness analysis). SETTING The setting was general (mixed medical/surgical) intensive care units (ICUs...

Micropollutants (MPs) are ubiquitous in wastewater and not effectively removed by the existing conventional treatment processes, resulting increased environmental pollution. Nowadays, dosing of powdered activated carbon (PAC) prior to membrane filtration has emerged as an advanced method for MPs removal. This study investigated agglomerate formation PAC stock suspension its influence on removal...