BACKGROUND gcrR gene acts as a negative regulator related to sucrose-dependent adherence in S. mutans. It is constructive to test the potential capacity of mutans with gcrR gene deficient in bacteria replacement therapy. METHODS In this study, we constructed the mutant by homologous recombination. The morphological characteristics of biofilms were analyzed by confocal laser scanning microscop...

Streptococcus mutans is the primary etiological agent of dental caries. The antimicrobial peptide D-Nal-Pac-525 was designed by replacing the tryptophans of the Trp-rich peptide Pac-525 with D-β-naphthyalanines. To assess the effect of D-Nal-Pac-525 on cariogenic bacteria, the activity of D-Nal-Pac-525 on the growth of S. mutans and its biofilm formation were examined. D-Nal- Pac-525 showed rob...

Background: Caries is an infectious disease accompanied by damage to the surface tissue of enamel, dentin and extends toward pulp. Microorganisms that have a role in formation caries, namely Streptococcus mutans. Rambutan leaves tin are plants antibacterial effect. This study aimed compare effects rambutan on bacteria mutans.
 Methods: In vitro experimental studies. A total 30 petri dishes...

Streptococcus mutans is a Gram-positive, non-motile, non-spore forming, catalasenegative, facultative anaerobic cocci bacterium commonly found in the human oral cavity, is a significant contributor to tooth decay (David et al., 2011). The mutans streptococci comprise a group of seven species, of which Streptococcus mutans and Streptococcus sobrinus are the predominant species isolated from huma...

Cover photo: Mutans streptococci on mitis salivarius bacitracin agar (MSB). To the left, colony representing Streptococcus sobrinus. In the middle and to the right, colonies representing Streptococcus mutans.

BACKGROUND To explore and analyse the association between biofilm and the genetic polymorphisms of scrA gene of EnzymeIIscr found in clinical isolates of Streptococcus mutans (S. mutans) from severe early childhood caries (S-ECC) in 3 years old children. METHODS Clinical strains of S. mutans were conserved from a previous study. Thirty strains of S. mutans from the S-ECC group and 30 strains ...

BACKGROUND The VicRK two-component signalling system regulates virulence and cariogenicity in Streptococcus mutans (S. mutans). The purpose of this study was to explore the genetic polymorphisms of the vicR and vicK genes, which are associated with dental caries in children with S. mutans. METHODS In this study, 121 (from each group) clinical S. mutans strains were isolated from caries-free c...

Dental caries is an infectious disease which still constitutes a public health concern. It begins at an early age and is caused mainly Streptococcus mutans (S. mutans). The aim of this study was to characterize the salivary humor immune response to S. mutans proteins in patients with caries, with history of caries and without caries, in order to determine which S. mutans proteins participate in...

INTRODUCTION Dental caries pose distinct challenges when it comes to determining their microbial etymology. Streptococcus mutans play an important role in dental caries. The aim of the present study was to compare oral microbiota in infants delivered by these different routes. A study was conducted on 40 infants. Swab sample collection was done for the detection of S. mutans. Our study indicate...

Adresa za dopisivanje Sérgio Luiz Pinheiro Rua Raul Gasparini, no 525, Bairro Panorama, Residencial Jardim das Palmeiras, Vinhedo – São Paulo Brazil – CEP 13280-000 tel: 55 11 992450090 / 55 19 38864258 [email protected] Sažetak Svrha: Željela se procijeniti moguća inhibicija rasta bakterije S. mutans na karioznom modelu koristeći se stakloionomernim cementom (GIC) pomiješanim s kazei...