نتایج جستجو برای: panss
تعداد نتایج: 1295 فیلتر نتایج به سال:
Secondary: The secondary objectives of this study were to compare the efficacy profiles of aripiprazole versus olanzapine based upon the results of efficacy scales (PANSS, Clinical Global Impression [CGI], and Montgomery-Asberg Depression Rating Scale [MADRS]), and to compare the safety and tolerability of aripiprazole versus olanzapine, and the response rate and discontinuation rate in patient...
مقدمه: هدف اصلی از پژوهش فعلی شناسایی ساختار عاملی مقیاس علائم مثبت و منفی در اختلالات طیف اسکیزوفرنی بود. روش: به همین منظور 150 بیمار مبتلا به اختلال های طیف اسکیزوفرنی (84 اسکیزوفرنی و 66 اسکیزوافکتیو) بستری در بیمارستانهای فاطمی و ایثار شهرستان اردبیل به شیوه در دسترس انتخاب شدند و با مقیاس نشانه های مثبت و منفی (panss) مورد بررسی قرار گرفتند. به منظور تحلیل اطلاعات از دو آزمون تحلیل عامل و...
Brexpiprazole (BPZ) is a novel antipsychotic drug in the category of serotonin-dopamine activity modulators (SDAMs). It expected to be effective treatment schizophrenia because its low side effects and ability reduce psychosis. However, clinical data Japan are still insufficient. We prescribed BPZ 41 schizophrenic patients; 9 dropped out 32 were retrospectively reviewed for psychiatric symptoms...
Recently, extensive efforts have been made to understand the rate of energy expenditure and the weight gain associated with atypical antipsychotic treatment, including identification of markers of obesity risk. In recent years, leptin, an adipocyte hormone, has gained significant interest in psychiatric disorders. S100B has been considered as a surrogate marker for astrocyte-specific damage in ...
There are diverse studies which afford evidences that risperidone is as effective second generation antipsychotics in treating positive symptoms and more treatment of negative symptoms. This study intended to find the clinical efficacy safety profile lurasidone comparing with risperidone, a drug common use nowadays. Patients aged between 18 60yrs, new onset who fulfil ICD-10 criteria for primar...
OBJECTIVE The pathophysiological mechanism of TD remains unknown. All previous studies, using the region-of-interest method, focused on basal ganglion areas, were with inconsistent results. This whole-brain voxel-based morphometry (VBM) study investigate the grey matter abnormality of TD and its correlates with clinical ratings. METHOD High resolution T1-weighted brain volumetric MRI from 25 ...
OBJECTIVE Investigators have reported that weight gain attributed to clozapine is associated with its clinical response. However, weight gain is a nonspecific physiological variable that, in itself, does not explain the mechanism underlying this relation. Alternatively, other biological variables that are often associated with weight gain, such as serum lipids, may assist in explaining this obs...
OBJECTIVE The use of an algorithm may facilitate measurement-based treatment and result in more rational therapy. We conducted a 1-year, open-label study to compare various outcomes of algorithm-based treatment (ALGO) for schizophrenia versus treatment-as-usual (TAU), for which evidence has been very scarce. METHODS In ALGO, patients with schizophrenia (Diagnostic and Statistical Manual of Me...
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