Pre-harvest desiccation of rapeseed crop may allow a more timely harvest as well as increase the speed and harvest operation efficiency as a second crop after rice. An effective desiccant which could be used as a harvest-aid with no negative effects on rapeseed yield and quality would be advantageous for oil seed crop producers and may reduce yield losses with no interferential effects on rice ...

A boronium-based paraquat analog undergoes reductions at more negative potentials than paraquat itself, making it a promising building block for electroactive materials.

Paraquat is a contact and non-selective herbicide which is used for controlling a wide range of terrestrial weeds and aquatic plants. A long-term contact with this xenobiotic can potentially lead to injuries in fishes as live non-target organisms. Therefore, the current study aimed to investigate the effect of sub-lethal toxicity of paraquat on the pathology of gill, liver, and spleen tissues i...

Paraquat, MPTP, and rotenone reproduce features of Parkinson's disease (PD) in experimental animals. The exact mechanisms by which these compounds damage the dopamine system are not firmly established, but selective damage to dopamine neurons and inhibition of complex I are thought to be involved. We and others have previously documented that the toxic metabolite of MPTP, MPP+, is transported i...

A rapid and sensitive method for the analysis of paraquat and diquat was developed using LC/MS, electrospray ionisation (ESI), positive ion mode, selective ion monitoring (SIM) large volume injections, and minimal sample preparation. No trace enrichment was required to obtain limits of detection (LOD) below 1 μg/L, which is well below the World Health Organisation (WHO) advisory value of 10 μg/...

The acute respiratory distress syndrome (ARDS) is an important and common medical emergency. This study aimed to explore the molecular mechanism on how paraquat induced the occurrence of acute respiratory distress syndrome (ARDS). Rats were selected and treated with saline and paraquat for 5 and 21 days, respectively. Lung tissues were selected. Quantitative RT-PCR and western blotting were per...

Paraquat is a weed killer which causes often fatal lung damage in humans and other animals. There is evidence that the pulmonary surfactant system is involved in the pathophysiology of respiratory failure after paraquat intoxication and, therefore, the possible therapeutic effect of intratracheal surfactant administration on gas exchange in rats with progressive lung injury induced by paraquat ...

Hyperoxia and paraquat ingestion are two clinical examples of lung injury thought to be mediated by oxidant mechanisms. An in vitro cytotoxicity assay using freshly explanted 51Cr-labeled lung tissue as the target was used to quantify the ability of hyperoxia and paraquat to directly injure lung parenchymal cells in an environment where indirect mechanisms such as recruitment of inflammatory ce...

Paraquat, an herbicide widely used in the agricultural industry, has been associated with lung, liver, and kidney toxicity in humans. In addition, it is linked to an increased risk of Parkinson's disease. For this reason, we had previously investigated the effects of paraquat in mice and showed that it influenced striatal nicotinic receptor (nAChR) expression but not nAChR-mediated dopaminergic...

Paraquat, a widely used herbicide, was found to cause a marked stimulation of lipid peroxidation in the human placental microsomes in vitro. Both NADPH and chelated iron were necessary to observe paraquat-stimulated lipid peroxidation. The malondialdehyde accumulation in the incubation medium increased with increase in time, protein and paraquat concentration. The reaction did not exhibit the i...