THE development of resistance to 5-fluorouracil (FU) in Ehrlich ascites carcin-oma (EAC) cells has been accompanied by decreases in the activities of uridine kinase (Reichard et al., 1962) or of uridine phosphorylase and deoxyuridine phos-phorylase (Reichard, Skold and Klein, 1959). These enzymes of the " uracil pathway " of pyrimidine biosynthesis are involved in the conversion of FU to its ac...

In this study, the finite element analysis of sigmoid functionally graded material (S-FGM) plates resting on orthotropic Pasternak elastic foundations with different angles is presented. For modelling, SAP2000 software package used in which required adjustments are made to obtain expected behaviour plate-foundation system. The plate modelled both using solid elements and layered shell by defini...

The author carries out a linguopoetic analysis of A. Voznesensky’s poem "Candle Sculptor" ("Skul’ptor Svechei") with particular focus on its lexical composition and textual associative meaning fields, as well symbolic, methaphoric intertextual connections. is devoted to the theme creativity, which appears in work spiritual burning requiring highest effort complete dedication from person. vocabu...