objectives the current study aimed to investigate h. pylori seropositivity in children with and without asthma. patients and methods this cross-sectional study was performed with 208 children aged 5- to 12-years-old (104 asthmatic subjects in the case group and 104 healthy individuals in the control group) who had been referred to the pediatric clinic of amir kabir hospital in arak, iran. h. py...

asthma environmental triggers play important roles in severity of disease. passive smoking could exacerbate asthma symptoms and enhance the decrease in lung function. cotinine levels could be a reflection of passive exposure to the cigarette both in adults and pediatrics. the aim of this study was to determine degree of association of asthma severity and cotinine level as a marker of passive sm...

Childhood asthma is influenced by multiple factors including genetic, socioeconomic, socio demographic and environmental factors. The symptoms of childhood asthma are observed to be variable. Some studies reported that asthma prevalence is disproportionately high among socially disadvantaged children. On the other hand, some reports found weak or no association between social disadvantage and c...

Method Children with asthma who were followed in our outpatient department of pediatric allergy unit were consecutively recruited. Asthma severity was graded according to NAEPP guidelines. Patients were categorized into two groups; children with intermittent and mild persistent asthma formed Group 1 (mild asthma) whereas children with moderate and severe persistent asthma formed Group 2 (severe...

Background: Asthma is a diverse inflammatory airway illness characterized by intermittent respiratory manifestations, and inhaled steroids (ICS) constitute the foundation of all asthma management regimens. The aim this study was to examine therapeutic efficacy Budesonide (BUD) regimens for recurrent wheeze treatment in pre-schoolers.
 Methods: This retrospective randomized controlled resea...

BACKGROUND AND OBJECTIVE Subcutaneous immunotherapy (SCIT) is approved in the United States for the treatment of pediatric asthma and rhinitis; sublingual immunotherapy (SLIT) does not have regulatory approval but is used in clinical practice. The objective of this study was to systematically review the evidence regarding the efficacy and safety of SCIT and SLIT for the treatment of pediatric a...

BackgroundAsthma exacerbations are highly prevalent in children, but only a few studies have examined the biologic mechanisms underlying this population.ObjectiveHigh-resolution metabolomics analyses were performed to understand differences metabolites children with exacerbating asthma who hospitalized pediatric intensive care unit for status asthmaticus. We hypothesized that compared similar p...