نتایج جستجو برای: pemphigus vulgaris
تعداد نتایج: 27288 فیلتر نتایج به سال:
Pemphigus vulgaris is a blistering autoimmune disease with suprabasal cleft formation, which is the most common autoimmune blistering disease in eastern countries, such as Middle East. Predisposition to pemphigus is linked to genetic factors. Tuberous sclerosis is also a genetic disorder of hamartoma formation in many organs, particularly the skin, brain, eye, kidney and heart. We report ...
Background: Pemphigus vulgaris has an obscure etiology; the presence of autoantibodies is coherent with autoimmune disease. Rituximab a monoclonal antibody that specifically targets CD20 antigen B lymphocytes, arisen as novel treatment approach for pemphigus vulgaris. Case presentation: A 39-year-old male patient presented three-month history mouth ulcers, poor oral hygiene accompanied heavy to...
introduction: pemphigus vulgaris (pv) is a chronic, serious autoimmune mucocutaneous bullous disease. oral lesions in pv may be extremely painful. this pain may adversely affect the patients’ oral intake and quality of life. this before-after clinical trial was designed to assess the pain relieving effects of single session of non-ablative, non-thermal co2 laser therapy (ntclt) in oral lesions ...
resulting in dysphagia A 44-year-old man was admitted to our institution because of the appearance of painful cutaneous, oral, and genital vesicles. His previous medical history was unremarkable. He had had pharyngitis treated with amoxicillin 1 month before the hospitalization. On physical examination, symmetrically erythematous plaques, covered with vesicles, were seen. Because of subsequent ...
Unit of Histology and Embryology, Department of Basic Biomedical Sciences, Faculty of Health Sciences, University of Talca, Talca, Chile, Department of Oral Diagnosis, School of Dentistry, State University of Campinas (UNICAMP), Piracicaba, São Paulo, Brazil, Mass Spectrometry Laboratory, Brazilian Biosciences National Laboratory CNPEM, Campinas, São Paulo, Brazil, Unit of Oral Pathology, Depar...
It has been suggested that anti-desmoglein autoantibody titers could be helpful in follow-up and therapeutic management of pemphigus patients. However, there is no consensus regarding the relationship between anti-desmoglein autoantibody titers and clinical activity of pemphigus.The aim of our study was to evaluate if clinical remission of pemphigus relates to the presence of anti-desmoglein au...
IMPORTANCE Oral lesions of pemphigus vulgaris are usually recalcitrant and respond slowly to treatments. Corticosteroid injection is considered to be the most effective local treatment in oral pemphigus vulgaris. However, intralesional corticosteroids are not effective in all remnant lesions. In 3 such patients with pemphigus vulgaris, we evaluated the utility of 2 injections (on days 1 and 15)...
There has been no previous clinical-immunological study of pemphigus in Spain. The aim of this study was to perform a retrospective analysis of pemphigus patients who had been followed for a period of 18 years in our centre. We characterized the autoantibody response, compared diagnostic assays and correlated the immunobiological data with phenotype and prognosis. Clinical, epidemiological and ...
BACKGROUND Human amnion membrane (HAM) was suggested to be a superior antigenic substrate for immunoblotting in detecting autoantibodies of autoimmune bullous skin diseases. OBJECTIVES To determine the properties of HAM as an antigenic substrate for the detection of autoantibodies in pemphigus vulgaris and bullous pemphigoid. METHODS Immunomapping and tandem liquid chromatography mass spect...
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