“Background” Peyronie’s disease which refers to an acquired penile deformity / curvature which occurs during erection may or may not be associated with pain. Peyronie’s disease is quite often a cause of worry to both the patient and his female partner. A number of treatment modalities have been available for the management of peyronie’s disease including: wait and see; oral medications; the now...

OBJECTIVE To assess the long-term patient's satisfaction and functional results of surgical correction for Peyronie's disease (PD) patients with penile curvature by 16-dot minimal tension placation and its modification in Chinese population. PATIENTS AND METHODS Between August 2004 and December 2008, 32 patients with PD underwent surgical correction of penile curvature by 16-dot minimal tensi...

The pathophysiology of erectile dysfunction after radical prostatectomy (RP) is believed to include neuropraxia, which leads to temporarily reduced oxygenation and subsequent structural changes in penile tissue. This results in veno-occlusive dysfunction, therefore, penile rehabilitation programmes focus on tissue oxygenation. Animal studies support the use of phosphodiesterase type 5 inhibitor...

The lumbosacral spinal network controlling penile erection is activated by information from peripheral and supraspinal origins. We tested the hypothesis that glutamate, released by sensory afferents from the genitals, activates this proerectile network. In anesthetized intact and T8 spinalized (i.e., freed from supraspinal inhibition) male rats, the parameters of electrical stimulation of the d...

The escape of a Brownian particle over a dichotomously fluctuating barrier is investigated for various shapes of the barrier. The problem of resonant activation is revisited with the attention on the effect of the barrier shape on optimal value of the mean escape time in the system. The characteristic features of resonant behavior are analyzed for situations when the barrier switches either bet...

BACKGROUND We report the results of microscopic penile revascularization in patients with arteriogenic erectile dysfunction. METHODS One patient with localized obstruction of the common penile artery underwent the Michal II penile revascularization, 13 patients underwent the Furlow-Fisher procedure, and 5 patients underwent the Hauri procedure. The mean age was 33.0 years and the mean follow-...

Peyronie's disease appears to be a condition of middle-aged men. In many of them, the disease is accompanied by erectile dysfunction, which, until recently, was attributed to penile deformity. Later, it turned out that the erectile dysfunction has the same causes as in men without Peyronie's disease with vascular and psychological components. In all cases, the pathology of the disease is charac...