BACKGROUND Enhanced recovery pathways are now widely used in elective surgical procedures. The feasibility of enhanced postoperative recovery pathways in emergency surgery for perforated peptic ulcer disease was investigated in this randomized controlled clinical trial. METHODS Patients with perforated peptic ulcer disease who underwent laparoscopic repair were randomized into 2 groups. Group...

Sarcoidosis is a multiorgan granulomatous disease of undetermined cause most commonly affecting young adults and typically characterized by pulmonary infiltrates, bilateral hilar lymphadenopathy, and cutaneous and ocular lesions. l Gastric involvement is the second most common site of gastrointestinal involvement after the liver, although the overall incidence of gastric sarcoidosis is still un...

In a prospective study designed to assess the effect of Helicobacter pylori eradication on peptic ulcer healing, 85 consecutive patients with H. pylori-positive peptic ulcer disease were treated with a triple therapy regimen consisting of colloidal bismuth subcitrate 120 mg four times daily for 28 days, with metronidazole 400 mg three times daily and tetracycline 500 mg three times daily for th...

BACKGROUND Despite a decreasing incidence of peptic ulcer disease, most previous studies report a stabile incidence of ulcer complications. We wanted to investigate the incidence of peptic ulcer complications in Sweden before and after the introduction of the proton pump inhibitors (PPI) in 1988 and compare these data to the sales of non-steroid anti-inflammatory drugs (NSAID) and acetylsalicyl...

BACKGROUND AND AIM In our previous study, the SLCO1B1 521TT genotype and the SLCO1B1*1b haplotype were significantly associated with the risk of peptic ulcer in patients taking low-dose aspirin (LDA). The aim of the present study was to investigate pharmacogenomic profile of LDA-induced peptic ulcer and ulcer bleeding. METHODS Patients taking 100 mg of enteric-coated aspirin for cardiovascula...

Gastric stump cancer was first reported as a disease entity by Balfour in 19221,6. It was defined initially as cancer that arises in the remnant stomach after five years of gastrectomy for benign disease such as peptic ulcer1,6,8. Another opinion includes ten-year latency period after primary operation for benign or malignant disease. Cancer recurrence in the stump after ten years of gastrectom...