The first detailed description of the morphology gastric ulcer was reported ~230 years ago, but mechanism has yet to be elucidated. Moreover, peptic ulcers, including duodenal and are currently considered an infectious disease caused by Helicobacter pylori, how infection leads ulceration remains elusive. To address these challenges, a recently published Complex Causal Relationship applied analy...

The following case of perforated duodenal ulcer in an infant is reported, not only on account of the raritv of the condition, but also because the symptoms and course presented differ somewhat from those in previouslv reported cases. Peptic ulcers are evidently not very rare in infants under one year of age, but onlv a few have been recorded in England. In Welch's1 collection of 6074 cases of p...

BACKGROUND The relation between Helicobacter pylori infection and non-steroidal anti-inflammatory drug (NSAID)-associated peptic ulcers remains unclear; in particular, it is not known whether H pylori plays a part in the healing and recurrence of these ulcers. AIMS To evaluate prospectively in a consecutive series of arthritis patients receiving longterm NSAID treatment the prevalence of pept...

INTRODUCTION: Ulcer is a common disorder of the gastrointestinal system, which causes much discomfort to patients, disrupting their daily routines and causes mental agony. Peptic ulcer is defined as a break off in the continuity of the mucosa of stomach or duodenum as a consequence of some medications like nonsteroidal anti-inflammatory drugs (NSAIDS), gastric acids and pepsin finally causes le...

BACKGROUND Peptic ulcer bleeding is a common and potentially fatal condition. For patients with bleeding peptic ulcers that display major endoscopic stigmata of recent hemorrhage, a combination of endoscopic and pharmacologic therapy is the current standard management. OBJECTIVE To show our experience with management of peptic ulcer bleeding. PATIENTS Patients who presented with gastrointes...

BACKGROUND It is presently not well understood to what extent peptic ulcer and gastric cancer represent related diseases. AIMS The objective of this study was to assess past occurrence of gastric and duodenal ulcers in patients with cancer of the gastric cardia or other parts of the stomach. METHODS The association between peptic ulcer and gastric cancer was studied among patients followed ...

O ur understanding of the pathophysiological features of peptic ulcer disease has rapidly evolved during the last century. Early understanding of gastric physiologic characteristics led to logical and time-tested surgical procedures aimed at acid reduction and a lowering of ulcer recurrence rates. A dramatic shift in treatment occurred with the recognition and growing knowledge of Helicobacter ...