Abstract Sunflower trypsin inhibitor‐1 (SFTI‐1) structure is used for designing‐grafted peptides as a possible therapeutic agent. The grafted peptide exhibits multiple conformations in solution due to the presence of proline peptide. To lock into major conformation solution, dibenzofuran moiety (DBF) was incorporated backbone structure, replacing Pro‐Pro sequence. NMR studies indicated solution...
