نتایج جستجو برای: percutaneous absorption

تعداد نتایج: 187163  

Journal: :Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 1994

Journal: :Journal of Occupational Medicine and Toxicology (London, England) 2006
Gintautas Korinth Tobias Weiss Jürgen Angerer Hans Drexler

There are only few studies about the relationship of skin lesions and the percutaneous uptake of hazardous substances in exposed workers. Several aromatic amines are well known carcinogens for humans and/or animals. This case report emphasizes the relevance of dermal absorption of the aromatic amine ortho-toluidine considering four workers with different skin status (healthy, erythematous and b...

2015
Hinda Dabboue Nicolas Builles Éric Frouin Dan Scott Jeanne Ramos Gilberte Marti-Mestres

For most xenobiotics, the rates of percutaneous absorption are limited by diffusion through the horny layer of skin. However, percutaneous absorption of chemicals may seriously increase when the skin is damaged. The aim of this work was to develop an in vitro representative model of mechanically damaged skins. The epidermal barrier was examined following exposure to a razor, a rotating brush, a...

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