PURPOSE To document the existence of idiopathic bilateral optic atrophy (BOA) in rhesus macaque monkeys and to characterize the structural and functional consequences of this condition. METHODS In vivo assessment of retinal and optic nerve structure included fundus biomicroscopy and stereophotography. Functional analyses included transient pattern-reversal electroretinography (PERG) and full-...

Explosive blasts associated with even mild traumatic brain injury can lead to substantial but delayed visual deficits, even in the absence of overt clinical presentation. There are two major challenges for these patients: lack of sensitivity in diagnostic testing to reveal the visual deficit and a dearth of viable treatment options to restore lost vision. In this issue of IOVS, Dutca et al. ind...

PURPOSE Effects of haloperidol on K(+) currents (IKs) of rat retinal ganglion cells (RGCs) were examined, with the hypothesis that its alteration of IKs explains alterations in the pattern electroretinogram (PERG). METHODS Fast blue was injected into superior colliculi of rats (3-8 days old) to identify RGCs under epifluorescence illumination after retrograde transport to retinas. Retinas wer...

The contrast transfer function (CTF) of the pattern electroretinogram (PERG) depends on temporal frequency. For transient stimulation it is fully linear; at faster stimulation rates it becomes strongly non-linear with an accelerated shape. In this study we investigated a range of stimulus parameters with the aim of studying the influence of temporal and spatial frequencies, as well as contrast ...

In this paper, we purpose a diagnostic procedure to identify the macular disease from pattern electroretionography (PERG) signals using artificial neural networks (ANN) methods. Multilayer feed forward ANN trained with a Levenberg Marquart backpropagation algorithm was implemented. The designed classification structure has about 96% sensitivity, 100% specifity and correct classification is calc...

PURPOSE To compare a new method for steady-state pattern electroretinogram (PERGx) with a validated method (PERGLA) in normal controls and in patients with optic neuropathy. METHODS PERGx and PERGLA were recorded in a mixed population (n = 33, 66 eyes) of younger controls (C1; n = 10, age 38 ± 8.3 years), older controls (C2; n = 11, 57.9 ± 8.09 years), patients with early manifest glaucoma (G...

Submit Manuscript | http://medcraveonline.com Abbreviations: ETS: Emission Trading Scheme; PMR: Partnership for Market Readiness; ISEGP: Integrated Solar Energy Generation Project; IWEP: Integrated Wind Energy Project; NPAC: National Plan of Action again Climate Change; UNFCCC: United Nations Framework Convention on Climate Change; NCCC: National Committee for Climate Change; REUNET: Renewable ...