Perinatal outcome of pregnancies caused by assisted reproduction technique (ART) is substantially worse when compared with pregnancies following natural conception. We investigated the possible risks of non-IVF ART on perinatal health. We conducted a retrospective cohort study with two exposure groups: a study group of pregnancies after controlled ovarian stimulation (COS), with or without arti...

Purpose: The purpose of this study was to investigate the impact of maternal, fetal and obstetric parameters in twin pregnancies due to chorionicity, perinatal morbidity and early neonatal mortality. Methods: Early neonatal outcome parameters were retrospectively analysed in 240 twin pregnancies (51 monochorionic [MC], 189 dichorionic [DC] twins) over a 7.5 years period. Beside chorionicity, we...

BACKGROUND Studies have demonstrated a higher risk of adverse outcomes among infants born or admitted during off-hours, as compared to office hours, leading to questions about quality of care provide during off-hours (weekend, evening or night). We aim to determine the relationship between off-hours delivery and adverse perinatal outcomes for subgroups of hospital births. METHODS This retrosp...

BACKGROUND Intrauterine growth restriction /retardation (IUGR) is defined as birth weight below the 10th percentile for a given gestational age. Placental insufficiency is the primary cause of intrauterine growth retardation in normally formed fetuses and can be identified using umbilical artery Doppler velocimetry which is a non-invasive technique. The objective of this study was to compare pe...

BACKGROUND The purpose of this paper was to investigate how well children's health until age 7 years can be predicted by perinatal outcome using routine health registers. METHODS Follow-up of one year cohort (N = 60192) was performed by record linkages with personal identification number. The data came from the 1987 Finnish Medical Birth Register, from six other national registers and from ed...

Introduction It was nearly 150 years ago that an association between perinatal events and brain injury was first reported, claiming that “the act of birth does occasionally imprint upon the nervous and muscular systems of the infantile organism very serious and peculiar evils” [1]. While a great deal is now known about this association and the pathophysiology behind it, the quantification of th...

OBJECTIVE To determine the obstetric and perinatal outcome in multiple pregnancies at a teaching hospital. STUDY DESIGN Cross-sectional observational study. PLACE AND DURATION OF STUDY Unit-A of the Department of Obstetrics and Gynaecology, PGMI, Lady Reading Hospital, Peshawar, from January to December 2009. METHODOLOGY The analysis included data on all women between 20 and 35 years of a...

OBJECTIVE The aim of this study was to investigate the influence of maternal age on perinatal and obstetric outcome in women aged 40-44 years and those 45 years or older and to estimate whether adverse outcome was related to intercurrent illness and pregnancy complications. METHODS National prospective, population-based, cohort study in women aged 40-44 years and those 45 years or older and i...

AIM The objective of the study was to examine whether cardiotocography can (CTG) predict asphyxia of the embryo, manifested as hypoxic-ischemic encephalopathy (HIE), and to what extent one can rely on CTG record. MATERIAL AND METHODS Retrospective research was carried out at the Clinic for Gynecology and Obstetrics UKC Tuzla and medical documentation from the history of mothers and newborns w...

INTRODUCTION The pathogenesis of perinatal hypoxic-ischemic brain damage is highly complex. OBJECTIVE The aim of this study was to assess the role of oxidative stress in hypoxic-ischemic brain injury and subsequent abnormal neurological outcome in infants with perinatal hypoxic-ischemic encephalopathy (HIE). We estimated perinatal oxidative brain damage measuring activity of glutathione perox...