Orthodontic forces for sliding tooth movement during space closure are applied at a distance from the centre of resistance of the teeth. For this reason, the teeth will tip until contacts are established between the archwire and diagonally opposite corners of the bracket wings. They will also rotate until the wire contacts opposite corners of the ligature tie or the buccal shield with self-liga...

PURPOSE The aim of this study was to investigate whether vitrification in the cryopreservation of periodontal ligament (PDL) cells could be useful for tooth banking. METHODS In step 1, primary cultured human PDL cells were cryopreserved in 100% conventional cryopreservation media and 100% vitrification media (ESF40 media) in different temperatures for 2 weeks. In step 2, a series of modified ...

Periodontitis is an inflammatory disease of bacterial origin that results in the progressive destruction of the tissues that support the teeth, specifically the gingiva, periodontal ligament, and alveolar bone. The diagnosis of periodontal disease currently relies almost exclusively on clinical parameters and traditional dental radiography. In this article, the authors review current diagnostic...

OBJECTIVES STRO-1 positive periodontal ligament cells (PDLCs) and unsorted PDLCs have demonstrated potential for periodontal regeneration, but the comparison between unsorted cells and the expanded STRO-1 sorted cells has never been reported. Additionally, Wnt3a is involved in cell proliferation thus may benefit in vitro PDLC expansion. The aim was to evaluate the effect of STRO-1 cell sorting ...

Before the accident, the tooth was held in place by fibres and cells called the periodontal ligament. The fibres were torn apart and many of the cells were damaged, either by the accident or because of the length of time out of the mouth. If the tooth has been out of the mouth more than 5 minutes, it will never be the same again. That means that if it is put back in, it will have to be extracte...

The periodontal ligament is the tissue that connects teeth to bone. The periodontal ligament is a fascinating tissue from a cell biologist's point of view, and because of its special properties and stem-cell content it has also come into the limelight in emerging fields of regenerative medicine. An increased range of genetically modified mouse models offer new tools for studying molecular mecha...

OBJECTIVE The aim of the present study was to analyze the influence of root canal and glass fiber post diameters on the biomechanical behavior of the dentin/cement/post interface of a root-filled tooth using 3D finite element analysis. MATERIAL AND METHODS Six models were built using micro-CT imaging data and SolidWorks 2007 software, varying the root canal (C) and the glass fiber post (P) di...

Both periodontal ligament and gingival tissue are thought to harbor cells with the ability to stimulate periodontal regeneration, i.e., formation of new bone, cementum, and connective tissue attachment. To understand further the role of these cells in the regenerative process, we compared human periodontal ligament cells and gingival fibroblasts, both derived from the same patient, same passage...

The purpose of this investigation was to analyse the influence of geometric and material parameters of a human canine on initial tooth mobility, and the stress and strain profiles in the periodontal ligament. While the material parameters of tooth and bony structures are known within an uncertain limit of approximately a factor of 10, values reported for the elasticity parameters of the periodo...

Periodontal disease is a chronic and irreversible disease that affects the supporting tissue of the teeth (gums, alveolar bone, cementum and periodontal ligament). The disease is often divided into two conditions: gingivitis and periodontitis. Gingivitis is inflammation of the gingiva, while periodontitis is inflammation of non-gingival tissue: periodontal ligament and alveolar bone (Harvey CE,...