PURPOSE The aim of the present study was to explore an association between IL-1B polymorphism and periodontal disease in patients with chronic periodontitis and subjects with aggressive periodontitis in a Polish population. In multivariate logistic regression the association of the following parameters: genotype, age, sex, smoking status, and approximal space plaque index (API) > 50% with the r...

Controlled and local drug delivery systems of anti-inflammatory agents are attracting increasing attention thanks to their possible pharmaceutical biomedical applications. These have extended therapeutic effects reduced side effects. The aim this work is synthesize a system composed SiO2 glass ketoprofen, an drug, by the sol–gel process. Two different percentages (5 15 wt%) entrapped in silica ...

BACKGROUND Ketorolac is approved for the relief of postoperative pain but concerns have been raised over a possible risk of serious adverse effects and death. Two regulatory reviews in Europe on the safety of ketorolac found the data were inconclusive and lacked comparison with other non-steroidal anti-inflammatory drugs. The aim of this study was to compare the risk of serious adverse effects ...

INTRODUCTION Mineral trioxide aggregate (MTA) is an endodontic material with different clinical applications e.g. root-end filling, pulp capping and perforation repair. It has been reported to possess antimicrobial and antifungal activities. The aim of this study was to examine the effect of White MTA on formalin-induced hyperalgesia in a rat with inflammatory pain. MATERIALS AND METHODS Infl...

The importance of the relative triplet excited state energies avobenzone (our phenacyl-like photolabile group) and ketoprofen photocaged drug) has been demonstrated by means spectroscopic experiments theoretical calculations.

BACKGROUND AND AIMS This study was designed to explore the relationship between periodontitis and diabetes mellitus (DM) in Uygur adults from Xinjiang. METHODS AND RESULTS Data were obtained using questionnaire and oral examination. Participants (48.87 ± 13.72 yr) were categorized into periodontitis and non-periodontitis groups in accordance with the chronic periodontitis diagnostic criteria....

BACKGROUND Total hip arthroplasty (THA) causes extensive tissue damage and severe pain. This study aimed to assess the analgesic efficacy, adverse effects (AEs), and safety of continuous intravenous (iv) oxycodone infusion with ketoprofen (injected into the iv line) in patients after THA, and to assay serum oxycodone levels. PATIENTS AND METHODS Fourteen patients, aged 59‒82 years with Americ...