نتایج جستجو برای: periorbital tumor

تعداد نتایج: 429436  

Journal: :Indian Dermatology Online Journal 2018

Journal: :Indian Journal of Dermatology, Venereology, and Leprology 2013

Journal: :Craniomaxillofacial Trauma & Reconstruction 2019

Journal: :Ophthalmology research: an international journal 2022

Trauma involving the eye, orbital and periorbital regions are commonly seen in cases of road traffic accidents, sports injuries physical assaults, but intraorbital / foreign bodies rare. Early presentation, history trauma, imaging help diagnosis. However, sometimes diagnosis is missed, particularly with late presentation a vague minor trauma non-metallic body. A missed body may present later in...

Journal: :The British journal of ophthalmology 1989
C N Smoot G B Krohel R S Smith

Three patients aged 15 to 40 years with fibromatosis of the periorbital region were studied. A history of acute onset, preceding trauma, and pain associated with a palpable mass were typical features. Rapid recurrence followed surgical excision. Misdiagnosis is common in this benign disease and may lead to unnecessary examinations for malignancy. Surgical excision or debulking of these masses i...

Journal: :The British journal of ophthalmology 1994
J Suharwardy

Periorbital necrotising fasciitis is an uncommon suppurative condition seen following trauma or in debilitated patients and frequently requires extensive debridement.' The basic pathological process is a cellulitis followed by suppuration and necrosis of the subcutaneous tissues and spread along the fascial planes of the sub-muscular aponeurotic system.2 The most frequently responsible pathogen...

2017
Akioh Yoshihara Hiroshi Mishima Naoshi Saito Yoshikazu Ugawa

A 16-year-old boy, with a history of juvenile myoclonic epilepsy, which had been treated with valproic acid since he was 9 years of age, presented with bilateral periorbital rash. His family had found him in a stupor state after groaning early the previous morning. The patient had a history of morning myoclonic seizures and absence seizures, but no history of generalized tonic-clonic seizures. ...

Journal: :BMJ case reports 2014
Vera Gomes Pereira Margarida Jacinto Jaime Santos Tiago Tribolet de Abreu

To cite: Pereira VG, Jacinto M, Santos J, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-201407 DESCRIPTION We report a case of a 62-year-old female patient with a 3-year history of non-traumatic palpebral and periorbital purpura (figure 1) and episodes of syncope. She had no other alteration on clinical examination. The laboratory study showed a com...

Journal: :The British journal of ophthalmology 1992
T E Lavy A M Fink

Necrobiosis lipoidica is a granulomatous skin condition typically occurring on the legs. A patient with this condition presented with gross bilateral induration of the eyelids sufficient to close both eyes.

Journal: :The New England journal of medicine 2015
William D Tap Zev A Wainberg Stephen P Anthony Prabha N Ibrahim Chao Zhang John H Healey Bartosz Chmielowski Arthur P Staddon Allen Lee Cohn Geoffrey I Shapiro Vicki L Keedy Arun S Singh Igor Puzanov Eunice L Kwak Andrew J Wagner Daniel D Von Hoff Glen J Weiss Ramesh K Ramanathan Jiazhong Zhang Gaston Habets Ying Zhang Elizabeth A Burton Gary Visor Laura Sanftner Paul Severson Hoa Nguyen Marie J Kim Adhirai Marimuthu Garson Tsang Rafe Shellooe Carolyn Gee Brian L West Peter Hirth Keith Nolop Matt van de Rijn Henry H Hsu Charles Peterfy Paul S Lin Sandra Tong-Starksen Gideon Bollag

BACKGROUND Expression of the colony-stimulating factor 1 (CSF1) gene is elevated in most tenosynovial giant-cell tumors. This observation has led to the discovery and clinical development of therapy targeting the CSF1 receptor (CSF1R). METHODS Using x-ray co-crystallography to guide our drug-discovery research, we generated a potent, selective CSF1R inhibitor, PLX3397, that traps the kinase i...

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