An orientated substratum has been implicated in the development and regeneration of axons and synapses. We prepared a basement membrane matrix from autogenous striated muscle, used it to repair the sciatic nerve in rats, then investigated the results by histology and electrophysiology. When treated grafts were coaxially aligned with the nerve fascicles functional recovery appeared within 30 day...

Various types of natural biological conduits have been investigated as alternatives to the current surgical standard approach for peripheral nerve injuries. Autologous nerve graft, the current gold standard for peripheral nerve damage, is limited by clinical challenges such as donor-site morbidity and limited availability. The purpose of this study was to evaluate the efficacy of using acellula...

INTRODUCTION Injuries of hand’s peripheral nerves constitute a major cause of functional disability, for being a frequent injury in economically active individuals. Today, the most used repair technique is the epiperineural suture, using microsurgical techniques. However, in injuries with segment loss or in chronic injuries when stump retraction occurs, the use of a graft is required. The obsta...

malignant peripheral nerve sheath tumor (mpnst), the principle malignancy of peripheral nerve origin, though rare in the general population, occurs with excessive frequency among patients with neurofi bromatosis. this tumor always arises in soft-tissues, usually found in the lower extremities and only 10-12% of all lesions occur in the head and neck region, which makes it a rare entity. the pri...

background: multiple sclerosis (ms) is known to affect essentially the central nervous system; however, peripheral nerve involvement, as an additional cause of disability, has been recently noticed. objectives: this study was aimed to perform detailed electrodiagnostic assessments in ms patients to evaluate peripheral nervous system involvement. materials and methods: a total of eighty ms patie...

Objectives: Measuring outcomes of intervention is one of the most important components of occupational therapy process. The Disabilities of Arm, Shoulder and hand (DASH) questionnaire is a valid and reliable instrument to measure outcomes of the occupational therapy services in the area of hand therapy. The study aims to measure outcomes from interventions of hand therapy in patients with the c...

PURPOSE To evaluate the applicability of the use of autogenous muscle treated in various ways, as a substitute of the nerve grafts. METHODS Rats were divided into seven groups that received, as a treatment for a standard nerve injury, the following types of grafts: fresh muscle, muscle fixed with 10% formaldehyde, muscle frozen in a freezer, muscle frozen in refrigerator, nerveless muscle, pe...

  Background: The standard method for repair of an injured peripheal nerve is epineural repair with separate sutures. Herein we describe a method in which the nerve is sutured with continous sutures. In fact this method has not been utilized for nerve repair previously and our purpose was to compare it to the standard method. If it proved to be successful it would replace the standard method in...

Traumatic injuries resulting in peripheral nerve lesions lead to important morbidity with devastating social and economic consequences. When the lesioned nerve cannot be sutured directly, a nerve graft is generally required to bridge the gap. Although autologous nerve grafting is still the first choice for reconstruction, it has the severe disadvantage of the sacrifice of a functional nerve. Re...

The landscape of available technology and surgical technique has changed over the last several decades, thus leading to changes in peripheral nerve repair algorithm. Neurorrhaphy is a common procedure; however, it well recognized that should be performed tensionless, preventing ability perform direct with gap. Historically, gaps were repaired autograft. However, autograft surgery been associate...