An optimal evacuation route plan has to be established to overcome the problem of poor coordination and uneven distribution of vehicles before or during disaster. This article introduces the evacuation vehicle routing problem (EVRP) as a new variant to the vehicle routing problem (VRP). EVRP is a process of moving vehicles from a vehicle location to the potentially flooded area (PFA), and from ...

In this presentation, the structural performance of fiber reinforced composite laminate Pi joints is studied through a progressive failure analysis (PFA) method. The bonded joint area that is the weakest link of the Pi joint structure is modeled using the discrete cohesive zone method (DCZM). The damage growth and failure of the bonded interface is modeled through an exponential decaying tracti...

Extending work of [14, 16, 26], we show there is a model of set theory in which normal spaces are collectionwise Hausdorff if they are either first countable or locally compact, and yet there are no first countable L-spaces or compact S-spaces. The model is one of the form PFA(S)[S], where S is a coherent Souslin tree.

On line quality control in industrial plants is an open field for signal processing applications. In this paper we present a realtime prototype for the detection of microcracks in tiles of wet ceramic by means of ultrasonics. We also describe the signal processing algorithm applied and particularly how the false alarm probability (PFA) may be controlled. Finally an experimental test shows the a...

BACKGROUND Friedreich's ataxia (FRDA) is the most common hereditary ataxia among caucasians. The molecular defect in FRDA is the trinucleotide GAA expansion in the first intron of the FXN gene, which encodes frataxin. No studies have yet reported frataxin protein and mRNA levels in a large cohort of FRDA patients, carriers and controls. METHODOLOGY/PRINCIPAL FINDINGS We enrolled 24 patients w...

Predictable Feature Analysis (PFA) [Richthofer and Wiskott, 2015] is an algorithm that performs dimensionality reduction on high dimensional input signal. It extracts those subsignals that are most predictable according to a certain prediction model. We refer to these extracted signals as predictable features. In this work we extend the notion of PFA to take supplementary information into accou...

BACKGROUND The relationship between biochemical aspirin resistance (AR) and functional outcome of acute ischemic stroke is uncertain. METHODS Prospectively, 269 patients with acute ischemic stroke were recruited. Their responsiveness to aspirin was evaluated by platelet function analyzer (PFA-100). All patients received blood tests for fibrinogen, high-sensitivity C-reactive protein (hs-CRP),...

BACKGROUND We evaluated the sensitivity, precision, and concordance of 4 assays designed to detect aspirin responsiveness or resistance. METHODS Twenty-nine healthy laboratory volunteers took 80 mg aspirin for 7 days, and a subset of volunteers took 325 mg aspirin for an additional 7 days. We measured platelet function by light transmission aggregometry with arachidonic acid, PFA-100, and Ver...

Obesity and inadequate sleep are among the most common causes of health problems in modern society. Thus, the discovery that orexin (hypocretin) neurons play a pivotal role in sleep/wake regulation, energy balance, and consummatory behaviors has sparked immense interest in understanding the regulatory mechanisms of these neurons. The local network consisting of neurons and astrocytes within the...