نتایج جستجو برای: ph responsive polymer

تعداد نتایج: 312864  

Journal: :iranian journal of basic medical sciences 0
elham khodaverdi department of pharmaceutics, school of pharmacy, mashhad university of medical sciences, mashhad, iran omid rajabi department of medicinal chemistry, school of pharmacy, mashhad university of medical sciences, mashhad, iran mohammad abdekhodai department of pharmaceutics, school of chemical engineering, sharif university, tehran, iran xiao yu wu department of pharmaceutics, school of pharmacy, university of toronto, toronto, canada

objective(s) in this study, a kind of ph sensitive composite membrane was prepared and drug permeation through it was investigated in terms of ph. rationale of this study originated from the fact that a ph change which may be a result of a disease state in the body can trigger drug release. materials and methods  here, a kind of ph sensitive composite membrane containing different nanoparticle ...

2016
Scarlet Milo Naing Tun Thet Dan Liu Jonathan Nzakizwanayo Brian V. Jones A. Toby A. Jenkins

We describe a novel infection-responsive coating for urinary catheters that provides a clear visual early warning of Proteus mirabilis infection and subsequent blockage. The crystalline biofilms of P. mirabilis can cause serious complications for patients undergoing long-term bladder catheterisation. Healthy urine is around pH 6, bacterial urease increases urine pH leading to the precipitation ...

Journal: :ACS nano 2012
Irina Drachuk Olga Shchepelina Milana Lisunova Svetlana Harbaugh Nancy Kelley-Loughnane Morley Stone Vladimir V Tsukruk

Saccharomyces cerevisiae yeast cells encapsulated with pH-responsive synthetic nanoshells from lightly cross-linked polymethacrylic acid showed a high viability rate of around 90%, an indication of high biocompatibility of synthetic pH-responsive shells. We demonstrated that increasing pH above the isoelectric point of the polymer shell leads to a delay in growth rate; however, it does not affe...

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