BACKGROUND Signal transducer and activator of transcription 1 (Stat1) potently regulates gene expression after stimulation by certain cytokines involved in tumorigenesis and host defenses. The present study investigated a novel role for Stat1 in foam cell formation and atherosclerosis. METHODS AND RESULTS Inhibition of Stat1 activity by a Stat1-specific DNA "decoy" oligomer transfected into d...

foam injection is becoming a standard conditioning agent when tunnelling with an earth-pressure balanced shield, resulting in an increasing interest in this technique. the technique is mostly based on empirical rules and experience. to be able to determine what foam and how may foam has to be injected for different soils, it is necessary to know the mechanical parameters of the foam-water-soil ...

A statistical predictive model is developed that describes the compression properties of phenolic foam reinforced with glass fibers. An analysis of variance is applied to determine the behavior of composite phenolic foam. The material variables used in the study are fiber length, fiber weight fraction and weight percentage of blowing agent. The responses analyzed are density, compressive modulu...

The phenomenological model of Khossravi and Connors (1992) has been adopted to calculate the electrophoretic mobility of drugs at different concentrations of solvents in a binary mixture. The accuracy and predictability of the model have been evaluated employing 14 experimental data sets by using average percentage mean deviation (APMD). The obtained APMD for correlative and predictive studies ...