The title compound, C(7)H(6)N(4)O(4), plays an important role in the synthesis of biologically active compounds. The planar hydrazone group is oriented at a dihedral angle of 8.27 (3)° with respect to the benzene ring. In the crystal structure, inter-molecular N-H⋯O and N-H⋯N hydrogen bonds link the mol-ecules.

four amidine nr2b-selective nmda receptor antagonists, n-( 2-methoxy benzyl) -3-phenyl-acrylamidine, n-[diduterio(2-methoxyphenyl) methyl]-3-phenyl-acrylamidine, n-benzyl-3-phenyl-acryl amidine and n-[diduterio(phenyl)methyl]-3-phenyl-acrylamidine, all fourlabeled with carbon-14 in the 1-position, have been synthesized as part of 5-step sequence fromba14co3.

A series of new 2-(phenylthio) benzoylaryl hydrazones were synthesized by acid-catalyzed condensation of hydrazide 3 with corresponding aldehydes. The chemical structures of the compounds were elucidated by FT-IR, 1H-NMR and Mass spectra. All newly synthesized compounds were evaluated for their antimycobacterial activities against Mycobacterium tuberculosis H37Rv using the microplate alamar blu...

The effect of alkyl substituents on the C-phenyl and/or the N-Phenyl ring of benzophenylhydroxamic acid on their molecular structure and hydrogen bonding has been investigated. The predominant configuration in CHCl3 is determined by steric and electronic effects. Substituents on the C-phenyl ring favor the cis configuration, while substituents in the N-phenyl ring favor a trans c...

Four acyl-hydrazones derived from 5-hydroxypicolinohydrazide and 4-hydroxybenzaldehyde (HL11), 2-fluoro-4-hydroxybenzaldehyde (HL12), 2,4-dihydroxybenzaldehyde (HL13) or 2-pyridinecarboxaldehyde (HL14) two hydrazones 2-hydrazino pyridine 4-dimethylaminobenzaldehyde (HL21) 4-diethylamino-2-hydroxybenzaldehyde (HL22) were synthesized their X-ray structures determined. Twelve rhenium(I) complexes ...

reaction between aromatic aldehydes and 3–methyl-1-phenyl-2-pyrazoline-5-one catalyzed by nano-sio2/hclo4 in water under reflux provided a simple and efficient route for the synthesis of 4-((5-hydroxy-3-methyl-1-phenyl-1h-pyrazol-4-yl)(aryl)methyl)-3-methyl-1-phenyl-1h-pyrazol-5-ol derivatives in high yields.