Sodium 2-(diphenylphosphino)ethyl phosphonate (1) was investigated as a stabilising agent for platinum nanoparticles (Pt-NPs) in aqueous solution. This phosphino phosphonate is known to stabilise rhodium nanoparticles (NPs) in water. Here we report that in the case of Pt-NPs this ligand is indirectly involved in the stabilisation mechanism and the actual stabilisation agent is the platinum comp...

Structure-activity relationships of amide-phosphonate derivatives as inhibitors of the human soluble epoxide hydrolase (sEH) were investigated. First, a series of alkyl or aryl groups were substituted on the carbon alpha to the phosphonate function in amide compounds to see whether substituted phosphonates can act as a secondary pharmacophore. A tert-butyl group (16) on the alpha carbon was fou...

In an attempt to interact natural bone and bone cells with biomaterials and to begin to develop modular tissue engineering scaffolds, substrates containing phosphonate groups were identified to mimic mineral-protein and natural polymer-protein interactions. In this study, we investigated poly(vinyl phosphonic acid) copolymer integration with existing materials as a graft-copolymer surface modif...

Organic-inorganic hybrid of cobalt phosphonate hollow nanostructured spheres were prepared in a water-ethanol system through a mild hydrothermal process in the absence of any templates using diethylenetriamine penta(methylene phosphonic acid) as bridging molecule. SEM, TEM and N2 sorption characterization confirmed a hollow spherical micromorphology with well-defined porosity. The structure and...

This article refers to:RETRACTED ARTICLE: A new mixed-ligand Co(II)-phosphonate framework: inhibited the wnt signaling pathway and exerted promotion activity on fracture rehabilitation

This account outlines the results obtained in the author’s laboratory on the application of phosphonate reagents in the synthesis of biologically active cyclopentanones and cyclopentenones. The synthesis and reactivity of 3-phosphorylmethyl-cycloalkenones is discussed as a platform for developing the first synthesis of enantiomeric isoterreins as well as the synthesis of racemic and optically a...

The preparation of lanthanide nitrate complexes [Ln(NO3)3{L}]n (Ln3+=La, Nd, Dy) supported by the octaethyl propane-1,1,3,3-tetrayltetrakis(phosphonate) (L) chelate ligand platform is presented. Re-crystallization these compounds from DMSO/THF led to a complete replacement multidentate phosphonate ester and formation exclusively DMSO-supported species [Ln(NO3)3(DMSO)4]. relative basicity model ...

Two new tetrametallic lanthanide-phosphonate complexes have been structurally and magnetically characterised. The {Dy4} complex is a single molecule magnet.