Sunlight is the ultimate driver of biosynthesis but photochemical steps late in biosynthetic pathways are very rare. They appear to play a role in the formation of certain furanocembranoids isolated from Caribbean corals. One of these compounds, intricarene, has been suspected to arise from an intramolecular 1,3-dipolar cycloaddition involving an oxidopyrylium. Here we show, by a combination of...

Photochemical machining (PCM), also known as photoetching, photofabrication or photochemical milling, is a non-traditional manufacturing method based on the combination of photoresist imaging and chemical etching. PCM uses techniques similar to those employed for the production of printed circuit boards and silicon integrated circuits. The PCM industry plays a valuable worldwide role in the pro...

A cursory look to the literature shows that only about 1% of the published papers classed as organic syntheses by Chemical Abstracts involve a photochemical step. On the other hand, in photochemistry courses it is often stated that excitation by light multiplies by 3 the accessible reaction paths, because the chemistry of the excited singlet and triplet states are added to that of the ground st...

The use of light as treatment dates back to ancient civilizations. However, it was the discovery green fluorescent protein that led a paradigm shift in our ability observe and study cellular processes. Applying investigation spatial temporal dynamics location, structure, function has enabled biological discoveries were previously unimaginable made significant contributions both understanding hu...