Key points † Optimizing tracheal sealing is of clinical interest: fluid leakage past the tube cuff plays an important role in the pathogenesis of VAP. † Tapered shaped tube cuff offering a sealing zone with reduced folds and channels is a new strategy to minimize fluid leakage past the tracheal tube cuff. † Tracheal tube cuffs made from PVC show much more and faster fluid leakage than cuffs mad...

Large supraphysiologic transmembrane electrical potentials are known to alter the molecular organization of the bilayer lipid component of cell membranes, leading to ionic permeabilization or "electroporation". Typically, membrane electroporation is followed by several orders of magnitude increases in electrical conductance and diffusive permeability to low-molecular-weight solutes. Electropora...

This study analyzes soil sealing and its repercussions in the loss of fertile soils, which are more appropriate for agriculture use. Also, soil sealing increases flood risk. The main objective is to estimate soil loss by sealing in the Guadarrama River Basin (Madrid, Spain) between 1961 and 2011. The combination of digital processing (Normalized Difference Vegetation Index (NDVI), principal com...

Bone remodeling is dependent on the dynamic equilibrium between osteoclast-mediated bone resorption and osteoblast-mediated osteogenesis. The sealing zone is an osteoclast-specific cytoskeletal structure, the integrity of which is critical for osteoclast-mediated bone resorption. To date, studies have focused mainly on the osteoprotegerin (OPG)‑induced inhibition of osteoclast differentiation t...

BACKGROUND Percutaneous endoscopic lumbar discectomy is a common surgical treatment for lumbar disc herniation, and percutaneous endoscopic interlaminar lumbar discectomy (PEID) is commonly used for direct decompression of L5-S1. Like microdiscectomy, recurrence of herniation after endoscopic discectomy is an important problem. In this study, we aimed to decrease the recurrence after PEID using...

BACKGROUND Blood presence in apical surgery can prevent the correct vision of the surgical field, change the physical properties of filling materials and reduce their sealing ability. OBJECTIVES To describe which are the most effective and safest haemostatic agents to control bleeding in patients undergoing apical surgery. MATERIAL AND METHODS We carried out a systematic review, using Medli...

This study evaluated the effectiveness of a dentin bonding agent as a barrier to prevent coronal microleakage and examined the effect of a eugenol-based sealer on the sealing ability of this resin adhesive. Fifty-one extracted human mandibular molars were incorporated in a model system using an oral streptococci as a microbial marker. Group 1 consisted of 15 teeth that were obturated with only ...

Vascular self-healing concrete is an innovative technology that can potentially improve the durability and longevity of structures. However, limited research available concerning this type compared to intrinsic or capsule-based healing. As rheology curing properties a healing agent dictate optimal design configuration vascular network, series testing procedures for evaluating agents further exp...

The study was carried out to evaluate and compare dentine margin microleakage of nano-filled resin composite restorations placed with a RMGIC using the co-cure technique and those placed with an ‘all-in-one’ self-etch DBA. In premolar teeth, that had to be extracted for orthodontic reasons, two proximal boxes with gingival margins placed in dentine were prepared. Restorations were inserted usin...

The edible film is an alternative that can be used as eco-friendly packaging material (biodegradable) a plastic substitute. in making films glucomannan, which dissolve easily but less elastic. development of the necessary edibles applied to foodstuffs requires combination ingredients are easy water. These materials derived from hydrocolloids or polysaccharides. research obtain formulated glucom...