By discovering how chemical compounds/xenobiotics cytotoxicity is affected when their metabolic pathways are inhibited or activated, the metabolic pathways that activate versus detoxify chemical compound can be identified. Reactive metabolites contributing to cytotoxicity can also be identified. In this lecture, the pretreatment of inhibitors and activators of xenobiotic metabolizing enzymes as...

background: one of the economic evaluation techniques involves calculation of willingness to pay (wtp) for a service to find out the value of that service from the clients’ perspective. this study estimated wtp for both breast cancer and osteoporosis screening and comparatively examined the contributing factors. in fact, the comparisons served to provide an exact analysis of individual attitude...

introducation: cancers are the third most common cause of death in iran. colorectal cancer is an ideal tumor for screening. therefore, early diagnosis through screening can reduce its prevalence and mortality. on the other hand, knowledge of practitioners about screening programs has a direct relationship with their performance. methods: in a cross-sectional-educational study, knowledge, attitu...

The range of mean QRS axes in the frontal plane was determined in electrocardiograms of subjects examined in a program of periodic health screening. Fifty-three of 5,163 individuals had a mean frontal QRS axis between -30 degrees and -60 degrees. Fourteen individuals had an axis between +110 degrees and +133 degrees. These findings suggest that individuals with no history of heart disease may m...

The screening of cancer is important in secondary prevention in clinical oncology. The cervical cancer screening by pelvic examination and Pap smear test is the standard practice worldwide. However, the coverage of the screening is an important consideration in public health. Some specific vulnerable populations are considered to have a low chance of having access to health care services includ...

background: cancer is the third most common cause of death in iran. colorectal cancer is an ideal tumor for screening. therefore, early diagnosis through screening can reduce its prevalence and mortality. on the other hand, knowledge of practitioners about screening programs has a direct relationship with their performance. methods: in the present cross-sectional-educational study, knowledge, a...

PURPOSE/OBJECTIVES To test the effectiveness of a community-based intervention to increase mammography screening for Korean American women. DESIGN Quasi-experimental, pre-/post-test, three-group design. SETTING Urban Korean American communities in Southern California. SAMPLE 141 Korean American women, aged 40-75, who had not had a mammogram in the previous 12 months. METHOD Two Korean c...

ebola is one of the members of filoviruses family. it causes severe hemorrhagic with the human mortality rate of 50-90%. in the initial steps of infection, it enters the host cell by glyco protein1 (gp1). gp1 is a big subunit with the molecular weight of 130 kda. its n-terminal domain is responsible for attaching the host cell. in the present study, a database containing 100.000 drug like chemi...