The nonlinear dynamics of an atomic force microcantilever (AFM) with an attached multi-walled carbon nanotube (MWCNT) tip is investigated experimentally and theoretically. We present the experimental nonlinear frequency response of a MWCNT tipped microcantilever in the tapping mode. Several unusual features in the response distinguish it from those traditionally observed for conventional tips. ...

We report the nanomechanical microcantilevers operated in vibration modes (oscillation) with use of RNA aptamers as receptor molecules for label-free detection of hepatitis C virus (HCV) helicase. The nanomechanical detection principle is that the ligand-receptor binding on the microcantilever surface induces the dynamic response change of microcantilevers. We implemented the label-free detecti...

Mycotoxins food contamination represents a serious risk for consumers health. They are 12 secondary metabolites of fungi that can be present in a wide range of foodstuffs. Ochratoxin A 13 (OTA) is one of the most toxic compound and it is classified as a possible carcinogenic molecule. 14 The harmful effects of OTA on human and animal health lead to a big boost to develop and 15 optimize highly ...

Microcantilevers modified with a self-assembled monolayer respond sensitively to specific ion concentrations. Here, we report the detection of trace amounts of CrO4(2-) using microcantilevers modified with a self-assembled monolayer of triethyl-12-mercaptododecylammonium bromide. The self-assembled monolayer was prepared on a silicon microcantilever coated with a thin layer of gold on one side....

The accessibility and binding affinity of DNA are two key parameters affecting the hybridization efficiency in surface-based biosensor technologies. Better accessibility will result in a higher hybridization efficiency. Often, mixed ssDNA and mercaptohexanol monolayers are used to increase the hybridization efficiency and accessibility of surface-bound oligonucleotides to complementary target D...

piezoelectric nanobeams having circular, rectangular and hexagonal cross-sections are synthesized and used in various nano structures; however, piezoelectric nanobeams with hexagonal cross-sections have not been studied in detail. in particular, the physical mechanisms of the surface effect and the role of surface stress, surface elasticity and surface piezoelectricity have not been discussed t...

In this study, a modified disk-shaped multiple-output piezoelectric transformer operated at the fundamental radial vibration mode has been presented. A derived equivalent circuit for the multioutput piezoelectric transformer was used to analyze the performance. Two piezoelectric transformers, a symmetrically electroded piezoelectric transformer with dual outputs and an asymmetrically electroded...

Recent experiments have shown that when specific biomolecular interactions are confined to one surface of a microcantilever beam, changes in intermolecular nanomechanical forces provide sufficient differential torque to bend the cantilever beam. This has been used to detect single base pair mismatches during DNA hybridization, as well as prostate specific antigen (PSA) at concentrations and con...