This study was undertaken to evaluate tissue transglutaminase (TG2) expression in guinea pig tissues, using an antibody against the guinea pig liver TG2. The tests were performed by means of a few immunohistochemical methods in specimens from: gut, skin, the lungs, lymph nodes, the heart, the thymus, the spleen, skeletal muscles of control guinea pigs and from inflamed skeletal muscles and skin...

Two polyhydroxysteroids and three steroidal saponins (pectiniosides A, B and C) were isolated as bioactive substances from Asterina pectinifera. These compounds inhibited the release of guinea-pig skin stratum corneum cells by 48-67% (control, 0%) at 2 mg/ml. It is suggested that the bioactivity of these compounds is connected with the remedial and preventive effects of an aqueous extract of A....

BACKGROUND Reactive oxygen species generated by ultraviolet light result in photocarcinogenic and photoaging changes in the skin. Antioxidants protect skin from these insults. OBJECTIVE This study defines formulation characteristics for delivering L-ascorbic acid into the skin to supplement the skin's natural antioxidant reservoir. METHODS L-ascorbic acid or its derivatives were applied to ...

BACKGROUND Biting habit of mosquitoes plays an important role in the epidemiology of mosquito-borne diseases. Mosquitoes use a set of elaborate sensory modalities to find their preferred hosts by exploiting cues emanating from a nearby host. It has been suggested that the chemical profile of skin can provide further support for anthropophilic mosquito species to find their suitable hosts. This ...

Non-ideal behaviour of mixed ions is disclosed in skin absorption experiments halide anions excised pig skin. Comparison pure and shows enhanced penetration chaotropic from solutions. An experimental design statistical analysis using a Scheffé {3,2} simplex-lattice allows investigating the full ternary diagram anion mixtures fluoride, bromide iodide. Synergism observed for iodide anions. A refi...

Epidermal slices from pig, human, and rat skin were treated with dilute buffered trypsin solution (0.005%, w/v), and suspensions of mixed basal and spinous cells were obtained in good yield. Total lipids accounted for approximately 8% of the pig, 10% of the human, and 20% of the rat epidermal cell (dry weight). Phospholipids in pig, human, and rat cells accounted for, respectively, 62%, 53%, an...

The demonstrated role of E- and P-selectin ligands in the recruitment of Th1 cells raises the question of tissue specificity determination by pathogenic T cells. We took advantage of the fact that chronic Th1-mediated inflammation in the scid/scid CD4+CD45RBhigh T cell transfer model can occur at multiple tissue sites, resembling inflammatory bowel disease in the colon and psoriasis in the skin...

Background: This study was designed to investigate the efficacy of Pentoxifylline (PTX) in the treatment of irradiated wounds. Materials and Methods: Ten female pigs of the Large White strain were used in these investigations. Six skin fields, 4 * 4 cm and separated from each other by 4 cm, were marked out on each flank and those on left flank were irradiated with 18Gy single dose of 250 kV X-r...

We present a batteryless, 27uW barely subcutaneous sensing platform using optical power and data links. We demonstrate an 8.1 mm x 3.2 mm implantable tag powered by an 850nm infrared source through the skin barrier. Measurements using pig skin indicate that optical power transfer through skin achieves a 4.9% efficiency, which is higher than mm scale inductive power links. As a proof-of-concept ...

1. In the skin of the tuberculous guinea pig while it is allergic, the spread of a vital dye, pontamine sky blue, and the drainage of the dye into the vascular system take place much more slowly than in the normal animal. 2. In the skin of moribund tuberculous guinea pigs, animals no longer allergic, dye spreads more rapidly than in the normal animal. 3. The spread of dye is somewhat restricted...