Myocardial remodeling is a major contributor in the development of heart failure (HF) after myocardial infarction (MI). Integrin-linked kinase (ILK), LIM-only adaptor PINCH-1, and α-parvin are essential components of focal adhesions (FAs), which are highly expressed in the heart. ILK binds tightly to PINCH-1 and α-parvin, which regulates FA assembly and promotes cell survival via the activation...

The stabilizing effect of a sheared axial flow is investigated in the ZaP Flow Z-pinch experiment at the University of Washington. Long-lived, Z-pinch plasmas are generated that are 100 cm long with a 1 cm radius and exhibit gross stability for many Alfvén transit times. Experimental measurements show a sheared flow profile that is coincident with the quiescent period during which magnetic fluc...

The aim of this study was to determine in monkeys if inactivation of dentate and lateral interposed deep cerebellar nuclei preferentially impairs certain movements relative to others. Constrained movements of the digits were trained with digits, hand, and elbow constrained in a cast. Simple movements were flexion of Thumb or Index. A compound movement was simultaneous flexion of Thumb+Index. An...

The S-matrix pinch technique is used to derive an effective gluon selfenergy to one-loop order, when the theory is quantized in the Coulomb gauge (CG) and in the temporal axial gauge (TAG). When the pinch contributions are added, the gluon self-energies calculated in CG and TAG turn out to be identical and coincide with the result previously obtained with covariant gauges. The issue of gauge in...

Gyrokinetic simulations of small-scale turbulent transport in a closed magnetic field-line plasma geometry are presented. The simulations are potentially applicable to dipolar systems such as the levitated dipole experiment (LDX) [J. Kesner, Plasma Phys. Rep. 23, 742 (1997).] and planetary magnetospheres, as well as simpler systems such as the Z pinch. We report here for the first time the exis...

INTRODUCTION In Parkinson's disease (PD), a resting tremor of the thumb may affect the flexor pollicis longus (FPL) and influence hand functions. We investigated the relationship between FPL tendon thickness and hand function in PD patients and compared these characteristics with those in healthy controls. METHODS The hand grip and pinch strengths were measured. The participants completed the...

The subcritical Organic Rankine Cycle (ORC) with 28 working fluids for waste heat recovery is discussed in this paper. The effects of the temperature of the waste heat, the critical temperature of working fluids and the pinch temperature difference in the evaporator on the optimal evaporation temperature (OET) of the ORC have been investigated. The second law efficiency of the system is regarde...