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We present a case of acute-onset diabetes insipidus in a 69-year-old man who had been treated for lung cancer. T1-weighted MR images showed a thickened pituitary stalk and absence of the normal high intensity of the posterior pituitary lobe. Dynamic imaging demonstrated poor enhancement in the posterior lobe, whereas the anterior lobe was strongly enhanced. Autopsy revealed that metastatic tumo...

Agressive pituitary adenomas are important in clinical practice. Analysis of their molecular mechanisms and genetic underpinnings also provides important lessons relevant to the fundamental biology of pituitary neoplasia. All too often, however, the proliferative and invasive features of pituitary tumors are downplayed, and such tumors are assumed, even by endocrinologists and oncologists (who ...

Pituitary carcinomas are rare primary adenohypophyseal tumors with cerebrospinal or extracranial metastasis. The present case, the first report of the disease in Korea, involved a 36-yr-old woman who presented with a 3-week history of headache. Brain magnetic resonance imaging revealed a 2.5-cm sellar and suprasellar mass showing heterogeneous enhancement with suspicious invasion of both cavern...

AIMS AND BACKGROUND To report the clinical outcomes of four patients with pituitary metastases treated with radiotherapy. METHODS Retrospective chart review of four cases. RESULTS The mean age of the patients was 66 years; two were women and two were men. The mean duration of symptoms at initial presentation of the primary tumor was 2.25 months. The location of the primary tumor was the bre...