Context. Plague is a serious health problem in northern Tanzania, with outbreaks since 2008 in two districts located in Rift Valley. There is dearth of knowledge on diversity of small mammal and flea fauna occurring in this plague focus. Knowledge on interactions between fleas and rodent species that harbour the plague bacterium, Yersinia pestis, is important for developing strategies for contr...

Intratracheal delivery of aerosolized monoclonal antibodies with specificity for Yersinia pestis LcrV and F1 antigens protected mice in a model of pneumonic plague. These data support the utility of inhaled antibodies as a fast-acting postexposure treatment for plague.

the treatment of the plague. It was naturally to be expected that by analogy with other infectious diseases (diphtheritis, typhus, entericus, &c.), that the manner cf searching out the method of treatment of the plague should be based on the cause of the disease itself and should essentially be of bacteriologic origin. This conclusion is quite logical, therefore the endeavour to prepare anti-pl...

a post-graduate lecture on plague, and in doing so read the chapters on plague in several standard textbooks of medicine. In these chapters the portions relating to the early researches on plague at the end of the 19th century and the beginning of the 20th century appeared rather unsatisfactory, and therefore a study was made of the original publications. This study made more clear the unsatisf...