3.1 Definition...........................................................................................2 3.2 Short Description..................................................................................2 3.3 State of R&D .......................................................................................2 3.3.1 Nanophase Materials ........................................................

Biotransformation systems, whether used for environmentally benign biocatalysis of synthetic reactions, or bioremediation of pollutants, require suitable biocatalysts and suitable bioreactor systems with particular characteristics. Our research focuses on the bioconversion of organic compounds, many of which are industrial residues, such as phenols, polyaromatic hydrocarbons, heterocyclic compo...

Nonpoint source nitrogen is recognized as a significant water pollutant worldwide. One of the major contributors is agricultural drainage line water. A potential method of reducing this nitrogen discharge to water bodies is the use of immobilized denitrifying sludge (IDS). Our objectives were to (1) produce an effective IDS, (2) determine the IDS reaction kinetics in laboratory column bioreacto...

Large-scale transient gene expression in mammalian cells is being developed for the rapid production of recombinant proteins for biochemical and preclinical studies. Here, the scalability of transient production of a recombinant human antibody in Chinese hamster ovary (CHO) cells was demonstrated in orbitally shaken disposable bioreactors at scales from 50 mL to 50 L. First, a small-scale multi...

Cardiovascular disease is the leading cause of morbidity and mortality in the Western World. The inability of fully differentiated, load-bearing cardiovascular tissues to in vivo regenerate and the limitations of the current treatment therapies greatly motivate the efforts of cardiovascular tissue engineering to become an effective clinical strategy for injured heart and vessels. For the effect...

Abstract This review article covers the topics of evaluation and experimental determination oxygen mass transfer coefficients ( k L a ) for their application in characterising bioreactors fermentations processes. The provides comparison different approaches determining bioreactors. Additionally, influence bioreactor design fermentation parameters on is discussed. aim to provide useful informati...

Background Over the last few decades, several studies have shown that plants can be a viable option for producing functional recombinant proteins with a wide range of structural characteristics [1]. In addition, the potential benefit for developing countries is a prominent feature that we have recently addressed [2]. Plant-produced recombinant proteins can already be considered a novel componen...

Anaerobic Treatment of Whey Permeate Using Upflow Sludge Blanket Bioreactors