The stability of Alfvén eigenmodes (AEs) is studied experimentally in the JET tokamak by observing the plasma response to antenna-driven frequency-sweeping perturbations at the plasma edge. During the 2008/9 experimental campaigns, the complete set of the new antennas was operated and AEs with toroidal mode numbers (n) in the intermediate-n range were excited under various plasma conditions. In...

There is an urgent need for biomarkers to enable early diagnosis of Alzheimer's disease (AD). It has recently been shown that a variant within the clusterin gene is associated with increased risk of AD and plasma levels of clusterin have been found to be associated with the risk of AD. We, therefore, investigated the diagnostic value of clusterin by quantifying clusterin using an ELISA in plasm...

The aim of the present study was to evaluate the reliability and effectiveness of directly determining endotoxin activity in plasma samples from kangaroos with lumpy jaw disease (LJD, n=15) and healthy controls (n=12). Prior to the present study, the ability of the commercially available automated handheld portable test system (PTS(TM)) to detect endotoxin activity in kangaroo plasma was compar...

thrombotic thrombocytopenic purpura is the result of multiple thrombus disseminated in small arterioles throughout the body. principle damage is in the endothelium of small vessels and capillaries. from 1982 to 1999, 28 patients (16 female and 12 male) have been treated for ttp. the outcome was evaluated for risk factors and prognosis. these patients were 18 to 69 years old. all had neurologica...

The breadth of diagnostic procedures that utilize cell free DNA (cfDNA) from human plasma has increased dramatically in recent years. Here, we confirm that tumor-derived cfDNA fragments are similar in size distribution to cfDNA derived from normal tissues. Therefore, collection procedures optimized with healthy donor specimens are likely to be applicable to the diagnosis and monitoring of many ...

In this study we show how hydrogen and helium lines modelling can be used to make a diagnostic of active and eruptive prominences. One motivation for this work is to identify the physical conditions during prominence activation and eruption. Hydrogen and helium lines are key in probing different parts of the prominence structure and inferring the plasma parameters. However, the interpretation o...

BACKGROUND Maternal plasma mRNA encoded by the PLAC4 gene (placenta-specific 4), which is transcribed from chromosome 21 in placental cells, is a potential marker for the noninvasive assessment of chromosome 21 dosage in the fetus. We evaluated the diagnostic sensitivities and specificities of 2 trisomy 21-screening approaches that use maternal plasma PLAC4 mRNA. METHODS We studied maternal p...

During the last decade, microRNAs (miRNAs) have been identified as potential biomarkers and therapeutic targets for multiple malignancies; yet, few studies exist on intrahepatic cholangiocarcinoma (ICC). In the present study, a miRNA microarray was applied to determine the significant miRNAs involved in ICC. miR-150 was found to be significantly downregulated in ICC. We further enrolled 15 ICC ...

Real dusty crystals are inhomogeneous due to the presence of external forces. We suggest approximations for calculations of different types of inhomoge-neous DC (chain and DC with a few slabs) in the equilibrium state. The results are in a good agreement with experimental results and can be used as an effective diagnostic method for many dusty systems.

BACKGROUND Triple-negative breast cancer (TNBC) is an aggressive cancer with unfavorable outcome and it is useful to explore noninvasive biomarkers for its early diagnosis. Here, we identified differentially expressed long noncoding RNAs (lncRNAs) in blood samples of patients with TNBC to assess their diagnostic value. METHODS Differential expression of lncRNAs in plasma of patients with TNBC...