Background: An elevated homocysteine level is an independent risk factor for cardiovascular disorders. Psoriatic patients have an increased risk of cardiovascular diseases; In addition, hyperhomocysteinemia is a complication of methotrexate treatment. We undertook a study to evaluate the plasma levels of homocysteine, vitamin B12 and folate in patients with psoriasis before and after short-term...

Apolipoprotein M (Apo-M) is a human novel protein of apolipoprotein classes and highly expressed in liver and kidney tissues. ApoM is mainly associated with high-density lipoprotein (HDL), and act as a chaperone for sphingosine-1-phosphate (S1P), promotes mobilization of cellular cholesterol, formation of larger-size of pre β-HDL, and a new biomarker in sepsis. The level of apoM in plasma/s...

Background: The cytokines have a major role in the inflammatory response to surgery and trauma. They have local effects of mediating and maintaining the inflammatory response to tissue injury, and also initiate some of the systemic changes which occur. IL-6 is one of the above mentioned cytokines, but it is not clear whether the duration of trauma or surgery has some effect on IL-6 level, so th...

Introduction: The role of different parts of the extended amygdala in metabolic signs of stress is not well understood. In the present study, we decided to evaluate the impact of the shell part of nucleus accumbens (NAc) on metabolic disturbance induced by electro foot shock stress using transient inactivation method in the rat.  Methods: Male Wistar rats (W: 230-250 g) were canuulated un...

  Gravid wild kutum broodstock, Rutilus frisii kutum, on their upstream migration to Valiabad River (northern Iran) were kept in captivity to allow them to ovulate (captive ripe). Then the impact of captivity on some reproductive and physiological parameters (i.e., plasma cortisol and glucose levels, fertilization percentage, gonadosomatic index and fecundity) were assessed and results were com...

  Gravid wild kutum broodstock, Rutilus frisii kutum, on their upstream migration to Valiabad River (northern Iran) were kept in captivity to allow them to ovulate (captive ripe). Then the impact of captivity on some reproductive and physiological parameters (i.e., plasma cortisol and glucose levels, fertilization percentage, gonadosomatic index and fecundity) were assessed and results were com...

n-terminal pro β-type natriuretic peptide (nt-probnp) is a valuable marker for monitoring the response to treatment in patients with heart failure. based on the clinically observed improvement of heart failure symptoms early after cardiac resynchronization therapy (crt), we sought to investigate whether crt induce any significant reduction in the plasma level of nt-probnp in three days after im...

high-performance liquid chromatography (hplc) methods employing ultraviolet (uv) detector are not sufficiently sensitive to measure the low plasma concentrations following single oral dose of imipramine. therefore, in the present study a simple, rapid and yet sensitive hplc method with uv detection was developed and validated for quantitation of imipramine in human plasma samples. an efficient ...