Partial thickness rotator cuff tears (PTRCTs) are a common pathology among shoulder disorders in people over 50 years. Treatment of PTRCTs remains controversial. Most studies on the treatment of PTRCTs have explained surgical techniques or outcomes; few studies have centralized on the conservative and new management of PTRCTs, like treatment with Platelet-rich plasma (PRP). These case series st...

Platelet concentrates for surgical use are autogenous regenerative preparations, produced by the centrifugation of the patient own blood sample. Most techniques are often regrouped inappropriately under the historical term of Platelet-Rich Plasma (PRP). Since 15 years, their use dramatically increased in many surgical fields, particularly in oral and maxillofacial surgery. The literature on thi...

Platelet-rich plasma (PRP) is highly concentrated auto logous solution of plasma prepared from a patient’s own blood. PRP contains platelets that are purported to release numerous growth factors that may be valuable in numerous dermatologic applications. We know the addition of platelets and their associated growth factors opened new possibilities, for the treatment of chronic skin ulcers. Ther...

The Sonoclot, a simple viscoelastometer, measures changes in the viscoelastic properties of plasma as it is recalcified. Platelet rich plasma (PRP) and platelet poor plasma (PPP) each have characteristic Sonoclot tracings. This technique was applied to evaluate the coagulability and platelet function, specifically, in PRP prepared from 53 normal term newborn cord bloods and whole blood from 17 ...

BACKGROUND Platelet-rich plasma (PRP) has more concentrated platelets than normal plasma (approximately 150-400×10(3) cell/dL). Platelets excrete several growth factors and cytokines that are associated with the healing and regeneration process. However, even though PRP is widely used, the mechanism or actual effect is presently unclear. Therefore, this study was performed to investigate the le...

OBJECTIVE Recent publications demonstrated improved outcomes during cardiac surgery when platelet rich plasma (PRP and platelet poor plasma (PPP) were applied during closure of the sternal and leg wounds [1,2]. These studies indicate a potential utility for PRP and PPP application in cardiothoracic surgery; however, further studies are necessary to truly measure the clinical efficacy of this in...

OBJECTIVE Muscle injuries are common, and their treatment requires costs and time off. Platelet rich plasma and low level laser therapy have been shown to be affordable and easy to use. The aim of this study was to evaluate the associated effects of low level laser therapy and platelet rich plasma on the treatment of the soleus muscle injured by strain in rats. METHODS Thirty-five rats were r...

Platelet-rich plasma (PRP) has been clinically used as an easily prepared growth factor cocktail that can promote wound healing, angiogenesis, and tissue remodeling. However, the therapeutic effects of PRP are still controversial, due partly to the lack of optimized and standardized preparation protocols. We used whole blood (WB) samples to optimize the preparation protocols for PRP, white bloo...

objective(s): platelet-rich plasma (prp) has recently emerged as a promising strategy in regenerative medicine due to its multiple endogenous growth factors. little is known about the role of prp as a promoter in chondrogenesis of human adipose derived stem cells (hadscs). the aim of this study was to determine whether prp may be considered as a natural and easy achievable source of growth fact...

Patients with severe uremia may have a bleeding tendency associated with a prolonged bleeding time and an adequate platelet count. We have tested the effects on platelet aggregation of three compounds that are found in increased concentration in the blood of patients with renal failure. The addition of urea was followed by an immediate, but transient, increase in optical density of platelet-ric...